Publications

All publications

S.T.Srinivasamurthy, V., Böttcher, D., Engel, J., Kara, S. & Bornscheuer, U. T. (2020). A whole-cell process for the production of ε-caprolactone in aqueous media. Process Biochemistry, 88, 22-30. https://doi.org/10.1016/j.procbio.2019.10.009

Assmann, M., Stöbener, A., Mügge, C., Gassmeyer, S. K., Hilterhaus, L., Kourist, R., Liese, A. & Kara, S. (2017). Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy. Reaction Chemistry & Engineering , 2, 531-540. https://doi.org/10.1039/C7RE00043J

Assmann, M., Mügge, C., Gassmeyer, S. K., Enoki, J., Hilterhaus, L., Kourist, R., Liese, A. & Kara, S. (2017). Improvement of the Process Stability of Arylmalonate Decarboxylase by Immobilization for Biocatalytic Profen Synthesis. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2017.00448

Berheide, M., Kara, S. & Liese, A. (2015). Reversibility of asymmetric catalyzed C–C Bond formation by benzoylformate decarboxylase. Catalysis Science & Technology, 5, 2418-2426. https://doi.org/10.1039/C4CY00171K

Berheide, M., Peper, S., Kara, S., Sing Long, W., Schenkel, S., Pohl, M., Niemeyer, B. & Liese, A. (2009). Influence of the hydrostatic pressure and pH on the asymmetric 2‐hydroxyketone formation catalyzed by Pseudomonas putida benzoylformate decarboxylase and variants thereof. Biotechnology and Bioengineering, 106(1), 18-26. https://doi.org/10.1002/bit.22650

Bisagni, S., Summers, B., Kara, S., Hatti-Kaul, R., Grogan, G., Mamo, G. & Hollmann, F. (2014). Exploring the substrate specificity and enantioselectivity of a Baeyer-Villiger monooxygenase from Dietzia sp. D5: oxidation of sulfides and aldehydes. Topics in Catalysis, 57(5), 366-375. https://doi.org/10.1007/s11244-013-0192-1

Bornadel, A., Hatti-Kaul, R., Hollmann, F. & Kara, S. (2016). Enhancing the productivity of the bi-enzymatic convergent cascade for ɛ-caprolactone synthesis through design of experiments and a biphasic system. Tetrahedron, 72(46), 7222-7228. https://doi.org/10.1016/j.tet.2015.11.054

Bornadel, A., Hatti-Kaul, R., Hollmann, F. & Kara, S. (2015). A bi-enzymatic convergent cascade for ε‐Caprolacton synthesis employing 1,6-hexanediol as a ‘double-smart cosubstrate. ChemCatChem, 7, 2442-2445. https://doi.org/10.1002/cctc.201500511

Buescher, N., Sayoga, G., Rübsam, K., Jakob, F., Schwaneberg, U., Kara, S. & Liese, A. (2019). Biocatalyst Immobilization by Anchor Peptides on an Additively Manufacturable Material. Organic Process Research & Development, 23(9), 1852-1859. https://doi.org/10.1021/acs.oprd.9b00152

De Santis, P., Meyer, L-E. & Kara, S. (2020). The Rise of Continuous Flow Biocatalysis – Fundamentals, Very Recent Developments and Future Perspectives. Reaction Chemistry & Engineering , 5(12), 2155-2184. https://doi.org/10.1039/D0RE00335B

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2017). Newly Designed and Discovered Monooxygenases for Synthesis of ECL. Poster session presented at The 19th triennial International Symposium on Flavins and Flavoproteins , Groningen, Netherlands. http://businessdocbox.com/Biotech_and_Biomedical/67687944-July-2-6-2017-groningen-the-netherlands.html

Engel, J., Opperman, D. J., Hollmann, F. & Kara, S. (2016). Characterisation of a Convergent Enzymatic Cascade for ε-Caprolactone Synthesis. Poster session presented at 8 th International Congress on Biocatalysis, Hamburg, Germany.

Engel, J., Siphamandla Mthetwa, K., Opperman, D. J. & Kara, S. (2019). Characterization of new Baeyer-Villiger monooxygenases for lactonizations in redox-neutral cascades. Molecular Catalysis , 468(May), 44-51. https://doi.org/10.1016/j.mcat.2019.02.006

Engel, J., Cordellier, A., Huang, L. & Kara, S. (2019). Enzymatic Ring‐Opening Polymerization of Lactones: Traditional Approaches and Alternative Strategies. ChemCatChem, 11(20), 4983-4997. https://doi.org/10.1002/cctc.201900976

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2018). Characterisation of BVMOs and Optimisation of the Convergent Cascade for Synthesis of ECL,. Poster session presented at 9th International Congress on Biocatalysis – BioCat 2018, Hamburg, Germany.

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2019). Optimisation of the Convergent Cascade for Synthesis of Epsilon-Caprolactone. Poster session presented at BioTrans 2019, Groningen, Netherlands.

Engel, J. (2020). Characterization of a redox-neutral convergent cascade for synthesis of epsilon-caprolactone. Aarhus Universitet.

Engel, J., Bornscheuer, U. T. & Kara, S. (2021). Kinetics Modeling of a Convergent Cascade Catalyzed by Monooxygenase–Alcohol Dehydrogenase Coupled Enzymes. Organic Process Research and Development, 25(3), 411-420. https://doi.org/10.1021/acs.oprd.0c00372

Hobisch, M., van Schie, M. M. C. H., Kim, J., Andersen, K. R., Alcalde, M., Kourist, R., Park, C. B., Hollmann, F. & Kara, S. (2020). Solvent‐Free Photobiocatalytic Hydroxylation of Cyclohexane. ChemCatChem, 12(16), 4009-4013. https://doi.org/10.1002/cctc.202000512

Hobisch, M., Holtmann, D., Gomes de Santos, P., Alcalde, M., Hollmann, F. & Kara, S. (Accepted/In press). Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations. Biotechnology Advances, [107615]. https://doi.org/10.1016/j.biotechadv.2020.107615

Hollmann, F. & Kara, S. (2014). Biokatalyse in unkonventionellen Reaktionsmedien. BioSpektrum, 20(1), 100-102. https://doi.org/10.1007/s12268-014-0412-7

Hollmann, F., Kara, S., Opperman, D. J. & Wang, Y. (2018). Biocatalytic synthesis of lactones and lactams. Chemistry - An Asian Journal, 13(23), 3601-3610. https://doi.org/10.1002/asia.201801180

Huang, L., Dominguez De Maria, P. & Kara, S. (2018). The ‘water challenge’: Opportunities and challenges of using oxidoreductases in non-conventional media. Chimica Oggi-Chemistry Today, 36(2). http://www.teknoscienze.com/tks_article/the-water-challenge-opportunities-and-challenges-of-using-oxidoreductases-in-non-conventional-media/

Huang, L., Romero, E., K. Messmann, A., Rudroff, F., Hollmann, F., W. Fraaije, M. & Kara, S. (2017). Nicotinamide adenine dinucleotide-dependent redox-neutral convergent cascade for lactonizations with type II flavin-containing monooxygenase. Advanced Synthesis & Catalysis, 359, 2142-2148. https://doi.org/10.1002/adsc.201700401

Huang, L., Sayoga, G. V., Hollmann, F. & Kara, S. (2018). Horse liver alcohol dehydrogenase-catalyzed oxidative lactamization of amino alcohols. A C S Catalysis, 8(9), 8680-8684. https://doi.org/10.1021/acscatal.8b02355

Huang, L., Tang, W., Röllig, R., S. Albers, F., W. Fraaije, M. & Kara, S. (2019). Convergent cascade catalyzed by monooxygenase – alcohol dehydrogenase fusion applied in organic media. ChemBioChem, 20(13), 1653-1658. https://doi.org/10.1002/cbic.201800814

Huang, L., Bittner, J. P., Dominguez De Maria, P., Jakobtorweihen, S. & Kara, S. (2020). Modeling Alcohol Dehydrogenase Catalysis in Deep Eutectic Solvent/Water Mixtures. ChemBioChem, 21(6), 811-817. https://doi.org/10.1002/cbic.201900624

Hümmer, M., Kara, S., Liese, A., Huth, I., Schrader, J. & Holtmann, D. (2018). Synthesis of (-)-menthol fatty acid esters in and from (-)-menthol and fatty acids – novel concept for lipase catalyzed esterification based on eutectic solvents. Molecular Catalysis , 458(A), 67-72. https://doi.org/10.1016/j.mcat.2018.08.003

Kara, S. & Schrittwieser, J. H. (2017). Enzymatische Reaktionskaskaden – „Fernbeziehungen“ und „Wohngemeinschaften“. BioSpektrum, 23(4), 468-470. https://doi.org/10.1007/s12268-017-0824-2

Kara, S., Schrittwieser, J. H., Gargiulo, S., Ni, Y., Yanase, H., Opperman, D. J. & van Berkel, W. J. H. (2015). Complete enzymatic oxidation of methanol to carbon dioxide: Towards more eco-efficient regeneration systems for reduced nicotinamide cofactors. Advanced Synthesis & Catalysis, 357(8), 1687-1691. https://doi.org/10.1002/adsc.201500173

Kara, S., Spickermann, D., Weckbecker, A., Leggewie, C., Arends, I. W. C. E. & Hollmann, F. (2014). Bioreductions catalyzed by an alcohol dehydrogenase in non-aqueous media. ChemCatChem, 6, 973-976. https://doi.org/10.1002/cctc.201300841

Kara, S., Schrittwieser, J. H., Hollmann, F. & B. Ansorge-Schumacher, M. (2014). Recent trends and novel concepts in cofactor-dependent biotransformations. Applied Microbiology and Biotechnology, 98(4), 1517-1529. https://doi.org/10.1007/s00253-013-5441-5

Kara, S., Spickermann, D., Schrittwieser, J. H., Weckbecker, A., Leggewie, C., Arends, I. W. C. E. & Hollmann, F. (2013). Access to lactone building blocks via horse liver alcohol dehydrogenase-catalyzed oxidative lactonization. A C S Catalysis, 3(11), 2536-2439. https://doi.org/10.1021/cs400535c

Kara, S., Schrittwieser, J. H. & Hollmann, F. (2013). Strategies for cofactor regeneration in biocatalyzed reductions. In E. Brenna (Ed.), Synthetic Methods for Biologically Active Molecules: Exploiting the Potential of Bioreductions (pp. 209-238). Wiley-VCH Verlag GmbH. https://doi.org/10.1002/9783527665785.ch08

Kara, S., Spickermann, D., Schrittwieser, J. H., Leggewie, C., van Berkel, W. J. H., Arends, I. W. C. E. & Hollmann, F. (2012). More efficient redox biocatalysis by utilising 1,4-butanediol as a ‘smart cosubstrate’. Green Chemistry and Sustainable Technology, 15, 330-335. https://doi.org/10.1039/C2GC36797A

Kara, S., Sing Long, W., Berheide, M., Peper, S., Niemeyer, B. & Liese, A. (2011). Influence of reaction conditions on the enantioselectivity of biocatalyzed C–C bond formations under high pressure conditions. Journal of Biotechnology, 152(3), 87-92. https://doi.org/10.1016/j.jbiotec.2011.01.020

Kara, S., J. Mueller, J. & Liese, A. (2011). Online analysis methods for monitoring of bioprocesses. Chimica Oggi-Chemistry Today, 29(2), 38-41. https://www.researchgate.net/publication/234015522_Online_analysis_methods_for_monitoring_of_bioprocesses

Kara, S., Anton, F., Solle, D., Neumann, M., Hitzmann, B., Scheper, T. & Liese, A. (2010). Fluorescence spectroscopy as a novel method for online analysis of biocatalytic C–C bond formations. Journal of Molecular Catalysis B: Enzymatic, 66, 124-129.

Kara, S. & Liese, A. (2010). Enzymatic C–C bond formation, asymmetric. In M. C. Flickinger (Ed.), Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology. (pp. 2034-2049). John Wiley & Sons, Inc.. https://doi.org/10.1002/9780470054581.eib272

Kara, S. & von Langermann, J. (2018). Prinzipien der angewandten Biokatalyse. In K-E. Jaeger, A. Liese & C. Syldatk (Eds.), Einführung in die Enzymtechnologie (pp. 225-242). Springer. https://doi.org/10.1007/978-3-662-57619-9_13

Kara, S. & Liese, A. (2019). Process considerations for the application of enzymes. In A. Vogel & O. May (Eds.), Industrial enzyme applications (pp. 71-94). Wiley. https://books.google.dk/books?id=eJGfDwAAQBAJ&pg=PA76&lpg=PA76&dq=%22Process+Considerations+for+the+Application+of+Enzymes%22&source=bl&ots=B5xnLGv7h9&sig=ACfU3U2rZsZwykthd-I_bErmKgtQPcc3AQ&hl=da&sa=X&ved=2ahUKEwj0ss-I8qTjAhXC-KQKHRcbBf4Q6AEwAHoECAIQAQ#v=onepage&q=%22Process%20Considerations%20for%20the%20Application%20of%20Enzymes%22&f=false

Kara, S. & von Langermann, J. (2020). Kompartimentierung bei den Enzymkaskaden: statisch oder Durchfluss. BioSpektrum, 26, 215-217. https://doi.org/10.1007/s12268-020-1348-8

Kara, S. & Rudroff, F. (Eds.) (2021). Enzyme Cascade Design and Modelling. Springer. https://doi.org/10.1007/978-3-030-65718-5

Kara, S. & Rudroff, F. (2021). Introduction: Enzyme Cascade Design and Modelling. In S. Kara & F. Rudroff (Eds.), Enzyme Cascade Design and Modelling (pp. 1-6). Springer. https://doi.org/10.1007/978-3-030-65718-5

Kara, S. & Rudroff, F. (2021). Perspectives: Enzyme Cascade Design and Modelling. In S. Kara & F. Rudroff (Eds.), Enzyme Cascade Design and Modelling (pp. 179-181). Springer. https://doi.org/10.1007/978-3-030-65718-5

Kochius, S., Ni, Y., Kara, S., Gargiulo, S., Schrader, J., Holtmann, D. & Hollmann, F. (2014). Light-accelerated biocatalytic oxidation reactions. ChemPlusChem, 79(11), 1554-1557. https://doi.org/10.1002/cplu.201402152

Kroutil, W., Reischauer, S., Bierbaumer, S., Winkler, C. K., Diaz-Rodriguez, A., J. Edwards, L., Kara, S., Mielke, T., Cartwright, J., Grogan, G., Pieber , B. & Schmermund, L. (2021). Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways. Angewandte Chemie, 60(13), 6965-6969. https://doi.org/10.1002/anie.202100164

Könst, P., Kara, S., Kochius, S., Holtmann, D., Arends, I. W. C. E., Ludwig, R. & Hollmann, F. (2013). Expanding the scope of laccase-mediator systems. ChemCatChem, 5(10), 3027-3032. https://doi.org/10.1002/cctc.201300205

Könst, P., Merkens, H., Kara, S., Kochius, S., Vogel, A., Zuhse, R., Holtmann, D., Arends, I. W. C. E. & Hollmann, F. (2012). Enantioselective oxidation of aldehydes catalyzed by alcohol dehydrogenase. Angewandte Chemie, 51(48), 9914-9917. https://doi.org/10.1002/anie.201203219

Meyer, L-E., Eser, B. E. & Kara, S. (Accepted/In press). Coupling light with biocatalysis for sustainable synthesis – very recent developments and future perspectives. Current Opinion in Green and Sustainable Chemistry. https://doi.org/10.1016/j.cogsc.2021.100496

Displaying results 1 to 50 out of 72

Revised 14.04.2021 -

Selin Kara