Publications

2023

Alphand, V., van Berkel, W. J. H., Jurkas, V., Kara, S., Kourist, R., Kroutil, W., Mascia, F., M. Nowaczyk, M., Paul, C. E., Schmidt, S., Spasic, J., Tamagnini, P. & Winkler, C. K. (2023). Exciting Enzymes: Current State and Future Perspective of Photobiocatalysis. ChemPhotoChem, 7(7), Artikel e202200325. https://doi.org/10.1002/cptc.202200325

De Santis, P., Wegstein, D., O. Burek, B., Patzsch, J., Alcalde, M., Kroutil, W., Z. Bloh, J. & Kara, S. (2023). Robust Light Driven Enzymatic Oxyfunctionalization Via Immobilization of Unspecific Peroxygenase. ChemSusChem, 16(23), Artikel e202300613. https://doi.org/10.1002/cssc.202300613

Domínguez de María, P., Kara, S. & Gallou, F. (2023). Biocatalysis in Water or in Non-Conventional Media? Adding the CO2 Production for the Debate. Molecules, 28(18), Artikel 6452. https://doi.org/10.3390/molecules28186452

Gkantzou, E., Weinhart, M. & Kara, S. (2023). 3D printing for flow biocatalysis. RSC Sustainability, 1(7), 1672-1685. https://doi.org/10.1039/d3su00155e

Jopp, S., Fleischhammer, T., Lavrentieva, A., Kara, S. & Meyer, J. (2023). Synthesis, biocompatibility, and antimicrobial properties of glucose-based ionic liquids. RSC Sustainability, 1(7), 1751-1764. https://doi.org/10.1039/d3su00191a

Meyer, L.-E., Horvath, D., Vaupel, S., Meyer, J., Alcalde, M. & Kara, S. (2023). A 3D printable synthetic hydrogel as an immobilization matrix for continuous synthesis with fungal peroxygenases. Reaction Chemistry & Engineering , 8(5), 984-988. https://doi.org/10.1039/d3re00058c

Milic, M., Domínguez de María, P. & Kara, S. (2023). A patent survey on the biotechnological production of 2,5-furandicarboxylic acid (FDCA): Current trends and challenges. EFB Bioeconomy Journal, 3, Artikel 100050. https://doi.org/10.1016/j.bioeco.2023.100050

Röllig, R., Paul, C. E., Rousselot-Pailley, P., Kara, S. & Alphand, V. (2023). Hybrid catalysis for enantioselective Baeyer-Villiger oxidation and stereoselective epoxidation: A Cp*Ir complex to fuel FMN and FAD reduction for flavoprotein monooxygenase modules. Reaction Chemistry & Engineering , 8(12), 3117-3123. https://doi.org/10.1039/d3re00411b

Santner, P., Chanquia, S. N., Petrovai, N., Vig Benfeldt, F., Kara, S. & Eser, B. E. (2023). Biocatalytic Conversion of Fatty Acids into Drop-in Biofuels: Towards Sustainable Energy Sources. EFB Bioeconomy Journal, 3, Artikel 100049. https://doi.org/10.1016/j.bioeco.2023.100049

Schweigerdt, A., D. Stöbener, D., Schäfer, A., Kara, S. & Weinhart, M. (2023). Impact of Amphiphilicity Balance in Hydroxy-Functional, Isomeric, Thermoresponsive Poly(meth)acrylates. Macromolecules, 56(21), 8602-8613. https://doi.org/10.1021/acs.macromol.3c01251

Semproli, R., Chanquia, S. N., Bittner, J. P., Müller, S., Domínguez de María, P., Kara, S. & Ubiali, D. (2023). Deep Eutectic Solvents for the Enzymatic Synthesis of Sugar Esters: A Generalizable Strategy? ACS Sustainable Chemistry & Engineering, 11(15), 5926-5936. https://doi.org/10.1021/acssuschemeng.2c07607

Vaupel, S., Mau, R., Kara, S., Seitz, H., Kragl, U. & Meyer, J. (2023). 3D printed and stimulus responsive drug delivery systems based on synthetic polyelectrolyte hydrogels manufactured via digital light processing. Journal of Materials Chemistry B, 28(11), 6547-6559. https://doi.org/10.1039/D3TB00285C

Vernet, G., Ma, Y., Zhang, N. & Kara, S. (2023). Cross-linked enzyme aggregates of fusion enzymes in microaqueous organic media. ChemBioChem, 24(8), Artikel e202200794. https://doi.org/10.1002/cbic.202200794

2022

Bittner, J. P., Zhang, N., Huang, L., Domínguez de María, P., Jakobtorweihen, S. & Kara, S. (2022). Impact of deep eutectic solvents (DESs) and individual DES components on alcohol dehydrogenase catalysis: Connecting experimental data and molecular dynamics simulations. Green Chemistry, 24(3), 1120-1131. https://doi.org/10.1039/D1GC04059F

Chanquia, S. N., Vernet Armengol, G. & Kara, S. (2022). Photobioreactors for cultivation and synthesis: Specifications, challenges, and perspectives. Engineering in Life Sciences, 22(12), 712-724. https://doi.org/10.1002/elsc.202100070

De Santis, P., Petrovai, N., Meyer, L.-E., Hobisch, M. & Kara, S. (2022). A holistic carrier-bound immobilization approach for unspecific peroxygenase. Frontiers in Chemistry, 10, Artikel 985997. https://doi.org/10.3389/fchem.2022.985997

Hobisch, M., De Santis, P., Serban, S., Basso, A., Byström, E. & Kara, S. (2022). Peroxygenase-Driven Ethylbenzene Hydroxylation in a Rotating Bed Reactor. Organic Process Research & Development, 26(9), 2761-2765. https://doi.org/10.1021/acs.oprd.2c00211

Jurkas, V., Winkler, C. K., Poschenrieder, S., Oliveira, P., C. Pacheco, C., A. Ferreira, E., Weissensteiner, F., De Santis, P., Kara, S., Kourist, R., Tamagnini, P. & Kroutil, W. (2022). Expression and activity of heterologous hydroxyisocaproate dehydrogenases in Synechocystis sp. PCC 6803 ΔhoxYH. Engineering Microbiology, 2(1), Artikel 100008. https://doi.org/10.1016/j.engmic.2021.100008

Jurkas, V., Weissensteiner, F., De Santis, P., Vrabl, S., A. Sorgenfrei, F., Bierbaumer, S., Kara, S., Kourist, R., P. Wangikar, P., Winkler, C. K. & Kroutil, W. (2022). Transmembrane Shuttling of Photosynthetically Produced Electrons to Propel Extracellular Biocatalytic Redox Reactions in a Modular Fashion. Angewandte Chemie, 61(40), Artikel e202207971. https://doi.org/10.1002/anie.202207971

Ma, Y., Zhang, N., Vernet, G. & Kara, S. (2022). Design of Fusion Enzymes for Biocatalytic Applications in Aqueous and Non-aqueous Media. Frontiers in Bioengineering and Biotechnology, 10, Artikel 944226. https://doi.org/10.3389/fbioe.2022.944226

Meyer, J., Meyer, L.-E. & Kara, S. (2022). Enzyme immobilization in hydrogels: A perfect liaison for efficient and sustainable biocatalysis. Engineering in Life Sciences, 22(3-4), 165-177. https://doi.org/10.1002/elsc.202100087

Meyer, L.-E., Andersen, M. B. & Kara, S. (2022). A Deep Eutectic Solvent Thermomorphic Multiphasic System for Biocatalytic Applications. Angewandte Chemie International Edition, 61(31), Artikel e202203823. https://doi.org/10.1002/anie.202203823

Meyer, L.-E., Fogtmann Hauge, B., Müller Kvorning, T., De Santis, P. & Kara, S. (2022). Continuous oxyfunctionalizations catalyzed by unspecific peroxygenase. Catalysis Science & Technology, 12(21), 6473-6485. https://doi.org/10.1039/D2CY00650B

Meyer, L.-E., Hobisch, M. & Kara, S. (2022). Process intensification in continuous flow biocatalysis by up and downstream processing strategies. Current Opinion in Biotechnology, 78, Artikel 102835. https://doi.org/10.1016/j.copbio.2022.102835

Milic, M., Byström, E., Domínguez de María, P. & Kara, S. (2022). Enzymatic Cascade for the Synthesis of 2,5-Furandicarboxylic Acid in Biphasic and Microaqueous Conditions: ‘Media-Agnostic’ Biocatalysts for Biorefineries. ChemSusChem, 15(9), Artikel e202102704. https://doi.org/10.1002/cssc.202102704

Nahuel Chanquia, S., Vig Benfeldt, F., Petrovai, N., Santner, P., Hollmann, F., Eser, B. E. & Kara, S. (2022). Immobilization and Application of Fatty Acid Photodecarboxylase in Deep Eutectic Solvents. ChemBioChem, 23(23), Artikel e202200482. https://doi.org/10.1002/cbic.202200482

Petermeier, P., Bittner, J. P., Müller, S., Byström, E. & Kara, S. (2022). Design of a green chemoenzymatic cascade for scalable synthesis of bio-based styrene alternatives. Green Chemistry, 24(18), 6889-6899. https://doi.org/10.1039/d2gc01629j

Röllig, R., Paul, C. E., Duquesne, K., Kara, S. & Alphand, V. (2022). Exploring the temperature effect on enantioselectivity of a Baeyer-Villiger biooxidation by the 2,5-DKCMO module: The SLM approach. ChemBioChem, 23(15), Artikel e202200293. https://doi.org/10.1002/cbic.202200293

Vernet, G., Hobisch, M. & Kara, S. (2022). Process intensification in oxidative biocatalysis. Current Opinion in Green and Sustainable Chemistry, 38, Artikel 100692. https://doi.org/10.1016/j.cogsc.2022.100692

Zhang, N., Müller, B., Kirkeby, T. Ø., Kara, S. & Loderer, C. (2022). Development of a thioredoxin based cofactor regeneration system for NADPH-dependent oxidoreductases. ChemCatChem, 14(7), Artikel e202101625. https://doi.org/10.1002/cctc.202101625

Zhang, N., Bittner, J. P., Fiedler, M., Beretta, T., De María, P. D., Jakobtorweihen, S. & Kara, S. (2022). Unraveling Alcohol Dehydrogenase Catalysis in Organic-Aqueous Biphasic Systems Combining Experiments and Molecular Dynamics Simulations. ACS Catalysis, 12(15), 9171-9180. https://doi.org/10.1021/acscatal.2c02881

2021

Bittner, J. P., Huang, L., Zhang, N., Kara, S. & Jakobtorweihen, S. (2021). Comparison and Validation of Force Fields for Deep Eutectic Solvents in Combination with Water and Alcohol Dehydrogenase. Journal of Chemical Theory and Computation, 17(8), 5322-5341. https://doi.org/10.1021/acs.jctc.1c00274

Chanquia, S. N., Valotta, A., Gruber-Woelfler, H. & Kara, S. (2021). Photobiocatalysis in continuous flow. Frontiers in Catalysis, 1. https://doi.org/10.3389/fctls.2021.816538/abstract

Engel, J., Bornscheuer, U. T. & Kara, S. (2021). Kinetics Modeling of a Convergent Cascade Catalyzed by Monooxygenase–Alcohol Dehydrogenase Coupled Enzymes. Organic Process Research and Development, 25(3), 411-420. https://doi.org/10.1021/acs.oprd.0c00372

Hobisch, M., Holtmann, D., Gomes de Santos, P., Alcalde, M., Hollmann, F. & Kara, S. (2021). Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations. Biotechnology Advances, 51, Artikel 107615. https://doi.org/10.1016/j.biotechadv.2020.107615

Hobisch, M., Spasic, J., Malihan-Yap, L., Barone, G. D., Castiglione, K., Tamagnini, P., Kara, S. & Kourist, R. (2021). Internal Illumination to Overcome the Cell Density Limitation in the Scale-up of Whole-cell Photobiocatalysis. ChemSusChem, 14(15), 3219-3225. https://doi.org/10.1002/cssc.202100832

Hobisch, M. & Kara, S. (2021). Automated Feeding and Fermentation Phase Transitions for the Production of Unspecific Peroxygenase by Pichia pastoris. bioRxiv. https://doi.org/10.1101/2021.07.29.454275

Kara, S. & Rudroff, F. (red.) (2021). Enzyme Cascade Design and Modelling. Springer. https://doi.org/10.1007/978-3-030-65718-5

Kara, S. & Rudroff, F. (2021). Introduction: Enzyme Cascade Design and Modelling. I S. Kara & F. Rudroff (red.), Enzyme Cascade Design and Modelling (s. 1-6). Springer. https://doi.org/10.1007/978-3-030-65718-5

Kara, S. & Rudroff, F. (2021). Perspectives: Enzyme Cascade Design and Modelling. I S. Kara & F. Rudroff (red.), Enzyme Cascade Design and Modelling (s. 179-181). Springer. https://doi.org/10.1007/978-3-030-65718-5

Kara, S. & Rudroff, F. (2021). Introduction. I Enzyme Cascade Design and Modelling (s. 1-6). Springer International Publishing. https://doi.org/10.1007/978-3-030-65718-5_1

Kara, S. & Rudroff, F. (2021). Perspectives. I Enzyme Cascade Design and Modelling (s. 179-181). Springer International Publishing. https://doi.org/10.1007/978-3-030-65718-5_11

Kara, S. & Rudroff, F. (2021). Preface. I Enzyme Cascade Design and Modelling (s. v-vi). Springer International Publishing.

Kroutil, W., Reischauer, S., Bierbaumer, S., Winkler, C. K., Diaz-Rodriguez, A., J. Edwards, L., Kara, S., Mielke, T., Cartwright, J., Grogan, G., Pieber , B. & Schmermund, L. (2021). Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways. Angewandte Chemie, 60(13), 6965-6969. https://doi.org/10.1002/anie.202100164

Meyer, L.-E., Eser, B. E. & Kara, S. (2021). Coupling light with biocatalysis for sustainable synthesis – very recent developments and future perspectives. Current Opinion in Green and Sustainable Chemistry, 31, Artikel 100496. https://doi.org/10.1016/j.cogsc.2021.100496

Petermeier, P. & Kara, S. (2021). Enzyme Cascade Reaction Engineering. I S. Kara & F. Rudroff (red.), Enzyme Cascade Design and Modelling (s. 109-124). Springer. https://doi.org/10.1007/978-3-030-65718-5

Petermeier, P., Fortuna, C., M. Hübschmann, K., Nahuel Bidart Costoya, G., Tørring, T., Teze, D., Welner, D. H. & Kara, S. (2021). Exploring the in Vitro Operating Window of Glycosyltransferase PtUGT1 from Polygonum tinctorium for a Biocatalytic Route to Indigo Dye. ACS Sustainable Chemistry & Engineering, 9(25), 8497-8506. https://doi.org/10.1021/acssuschemeng.1c01536

Petermeier, P. & Kara, S. (2021). Enzyme cascade reaction engineering. I Enzyme Cascade Design and Modelling (s. 109-124). Springer International Publishing. https://doi.org/10.1007/978-3-030-65718-5_7

Röllig, R., Paul, C. E., Claeys-Bruno, M., Duquesne, K., Kara, S. & Alphand, V. (2021). Divorce in the two-component BVMO family: the single oxygenase for enantioselective chemo-enzymatic Baeyer–Villiger oxidations. Organic & Biomolecular Chemistry, 19(15), 3441-3450. https://doi.org/10.1039/D1OB00015B

Santner, P., Szabó, L. K., Chanquia, S. N., Høj Merrild, A., Hollmann, F., Kara, S. & Eser, B. E. (2021). Optimization and Engineering of Fatty Acid Photodecarboxylase for Substrate Specificity. ChemCatChem, 13(18), 4038-4046. https://doi.org/10.1002/cctc.202100840

Schmermund, L., Reischauer, S., Bierbaumer, S., Winkler, C. K., Diaz-Rodriguez, A., J. Edwards, L., Kara, S., Mielke, T., Cartwright, J., Grogan, G., Pieber, B. & Kroutil, W. (2021). Switching Between Enantiomers by Combining Chromoselective Photocatalysis and Biocatalysis. ChemRxiv. file:///C:/Users/Mogens/Downloads/PhotoCat-switching_product_ChemRxiv.pdf

Zhang, N., Steininger, F., Meyer, L.-E., Koren, K. & Kara, S. (2021). Can Deep Eutectic Solvents Sustain Oxygen-Dependent Bioprocesses? Measurements of Oxygen Transfer Rates. ACS Sustainable Chemistry & Engineering, 9(25), 8347–8353. https://doi.org/10.1021/acssuschemeng.1c03547

2020

Chanquia, S. N., Huang, L., Garcia Linares, G., Dominguez de Maria, P. & Kara, S. (2020). Deep Eutectic Solvents as Smart Cosubstrate in Alcohol Dehydrogenase-Catalyzed Reductions. Catalysts, 10(9), 1-8. Artikel 1013. https://doi.org/10.3390/catal10091013

De Santis, P., Meyer, L.-E. & Kara, S. (2020). The Rise of Continuous Flow Biocatalysis – Fundamentals, Very Recent Developments and Future Perspectives. Reaction Chemistry & Engineering , 5(12), 2155-2184. https://doi.org/10.1039/D0RE00335B

Engel, J. (2020). Characterization of a redox-neutral convergent cascade for synthesis of epsilon-caprolactone. [Ph.d.-afhandling, Aarhus Universitet]. Aarhus Universitet.

Hobisch, M., van Schie, M. M. C. H., Kim, J., Andersen, K. R., Alcalde, M., Kourist, R., Park, C. B., Hollmann, F. & Kara, S. (2020). Solvent‐Free Photobiocatalytic Hydroxylation of Cyclohexane. ChemCatChem, 12(16), 4009-4013. https://doi.org/10.1002/cctc.202000512

Huang, L., Bittner, J. P., Dominguez De Maria, P., Jakobtorweihen, S. & Kara, S. (2020). Modeling Alcohol Dehydrogenase Catalysis in Deep Eutectic Solvent/Water Mixtures. ChemBioChem, 21(6), 811-817. https://doi.org/10.1002/cbic.201900624

Kara, S. & von Langermann, J. (2020). Kompartimentierung bei den Enzymkaskaden: statisch oder Durchfluss. BioSpektrum, 26(2), 215-217. https://doi.org/10.1007/s12268-020-1348-8

Schmermund, L., Bierbaumer, S., Schein, V. K., Winkler, C. K., Kara, S. & Kroutil, W. (2020). Extending the Library of Light‐Dependent Protochlorophyllide Oxidoreductases and their Solvent Tolerance, Stability in Light and Cofactor Flexibility. ChemCatChem, 12(16), 4044-4051. https://doi.org/10.1002/cctc.202000561

S.T.Srinivasamurthy, V., Böttcher, D., Engel, J., Kara, S. & Bornscheuer, U. T. (2020). A whole-cell process for the production of ε-caprolactone in aqueous media. Process Biochemistry, 88, 22-30. https://doi.org/10.1016/j.procbio.2019.10.009

2019

Buescher, N., Sayoga, G., Rübsam, K., Jakob, F., Schwaneberg, U., Kara, S. & Liese, A. (2019). Biocatalyst Immobilization by Anchor Peptides on an Additively Manufacturable Material. Organic Process Research & Development, 23(9), 1852-1859. https://doi.org/10.1021/acs.oprd.9b00152

Dominguez de Maria, P., Guajardo, N. & Kara, S. (2019). Enzyme catalysis: In DES, with DES, and in the presence of DES. I D. J. Ramón & G. Guillena (red.), Deep Eutectic Solvents: Synthesis, Properties, and Applications (s. 257-271). Wiley. https://doi.org/10.1002/9783527818488.ch13

Engel, J., Siphamandla Mthetwa, K., Opperman, D. J. & Kara, S. (2019). Characterization of new Baeyer-Villiger monooxygenases for lactonizations in redox-neutral cascades. Molecular Catalysis , 468(May), 44-51. https://doi.org/10.1016/j.mcat.2019.02.006

Engel, J., Cordellier, A., Huang, L. & Kara, S. (2019). Enzymatic Ring‐Opening Polymerization of Lactones: Traditional Approaches and Alternative Strategies. ChemCatChem, 11(20), 4983-4997. https://doi.org/10.1002/cctc.201900976

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2019). Optimisation of the Convergent Cascade for Synthesis of Epsilon-Caprolactone. Poster-session præsenteret på BioTrans 2019, Groningen, Holland.

Huang, L., Tang, W., Röllig, R., S. Albers, F., W. Fraaije, M. & Kara, S. (2019). Convergent cascade catalyzed by monooxygenase – alcohol dehydrogenase fusion applied in organic media. ChemBioChem, 20(13), 1653-1658. https://doi.org/10.1002/cbic.201800814

Kara, S. & Liese, A. (2019). Process considerations for the application of enzymes. I A. Vogel & O. May (red.), Industrial enzyme applications (s. 71-94). Wiley. https://doi.org/10.1002/9783527813780.ch1_4

Pätzold, M., Siebenhaller, S., Kara, S., Liese, A., Syldatk, C. & Holtmann, D. (2019). Deep Eutectic Solvents as Efficient Solvents in Biocatalysis. Trends in Biotechnology, 37(9), 943-959. https://doi.org/10.1016/j.tibtech.2019.03.007

2018

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2018). Characterisation of BVMOs and Optimisation of the Convergent Cascade for Synthesis of ECL,. Poster-session præsenteret på 9th International Congress on Biocatalysis – BioCat 2018, Hamburg, Hamborg, Tyskland.

Hollmann, F., Kara, S., Opperman, D. J. & Wang, Y. (2018). Biocatalytic synthesis of lactones and lactams. Chemistry - An Asian Journal, 13(23), 3601-3610. https://doi.org/10.1002/asia.201801180

Huang, L., Dominguez De Maria, P. & Kara, S. (2018). The ‘water challenge’: Opportunities and challenges of using oxidoreductases in non-conventional media. Chimica Oggi-Chemistry Today, 36(2), 48-56. http://www.teknoscienze.com/tks_article/the-water-challenge-opportunities-and-challenges-of-using-oxidoreductases-in-non-conventional-media/

Huang, L., Sayoga, G. V., Hollmann, F. & Kara, S. (2018). Horse liver alcohol dehydrogenase-catalyzed oxidative lactamization of amino alcohols. A C S Catalysis, 8(9), 8680-8684. https://doi.org/10.1021/acscatal.8b02355

Hümmer, M., Kara, S., Liese, A., Huth, I., Schrader, J. & Holtmann, D. (2018). Synthesis of (-)-menthol fatty acid esters in and from (-)-menthol and fatty acids – novel concept for lipase catalyzed esterification based on eutectic solvents. Molecular Catalysis , 458(A), 67-72. https://doi.org/10.1016/j.mcat.2018.08.003

Kara, S. & von Langermann, J. (2018). Prinzipien der angewandten Biokatalyse. I K.-E. Jaeger, A. Liese & C. Syldatk (red.), Einführung in die Enzymtechnologie (s. 225-242). Springer. https://doi.org/10.1007/978-3-662-57619-9_13

pesci, L., Kara, S. & Liese, A. (2018). Enzymkinetik. I K.-E. Jaeger, A. Liese & C. Syldatk (red.), Einführung in die Enzymtechnologie (s. 53-75). Springer. https://doi.org/10.1007/978-3-662-57619-9_4

2017

Assmann, M., Stöbener, A., Mügge, C., Gassmeyer, S. K., Hilterhaus, L., Kourist, R., Liese, A. & Kara, S. (2017). Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy. Reaction Chemistry & Engineering , 2(4), 531-540. https://doi.org/10.1039/C7RE00043J

Assmann, M., Mügge, C., Gassmeyer, S. K., Enoki, J., Hilterhaus, L., Kourist, R., Liese, A. & Kara, S. (2017). Improvement of the Process Stability of Arylmalonate Decarboxylase by Immobilization for Biocatalytic Profen Synthesis. Frontiers in Microbiology, 8(MAR), Artikel 448. https://doi.org/10.3389/fmicb.2017.00448

Engel, J., Mthethwa, K. S., Opperman, D. J. & Kara, S. (2017). Newly Designed and Discovered Monooxygenases for Synthesis of ECL. Poster-session præsenteret på The 19th triennial International Symposium on Flavins and Flavoproteins , Groningen, Holland. http://businessdocbox.com/Biotech_and_Biomedical/67687944-July-2-6-2017-groningen-the-netherlands.html

Huang, L., Romero, E., K. Messmann, A., Rudroff, F., Hollmann, F., W. Fraaije, M. & Kara, S. (2017). Nicotinamide adenine dinucleotide-dependent redox-neutral convergent cascade for lactonizations with type II flavin-containing monooxygenase. Advanced Synthesis & Catalysis, 359(12), 2142-2148. https://doi.org/10.1002/adsc.201700401

Kara, S. & Schrittwieser, J. H. (2017). Enzymatische Reaktionskaskaden – „Fernbeziehungen“ und „Wohngemeinschaften“. BioSpektrum, 23(4), 468-470. https://doi.org/10.1007/s12268-017-0824-2

Mthethwa, K. S., Kassier, K., Engel, J., Kara, S., Smit, M. S. & Opperman, D. J. (2017). Fungal BVMOs as alternatives to cyclohexanone monooxygenase. Enzyme and Microbial Technology, 11-17. Artikel 106.

pesci, L., Gurikow, P., Liese, A. & Kara, S. (2017). Amine-mediated enzymatic carboxylation of phenols using CO2 as substrate. Biotechnology Journal. https://doi.org/10.1002/biot.201700332

pesci, L., Baydar, M., Glueck, S., Faber, K., Liese, A. & Kara, S. (2017). Development and scaling-up of the fragrance compound 4‑ethylguaiacol synthesis via a two-step chemo-enzymatic reaction sequence. Organic Process Research & Development, 21(1), 85-93. https://doi.org/10.1021/acs.oprd.6b00362

Rauch, M., Schmidt, S., Arends, I. W. C. E., Oppelt, K., Kara, S. & Hollmann, F. (2017). Photocatalytic alcohol oxidation using LED light sources. Green Chemistry, 19(2), 376-379. https://doi.org/10.1039/C6GC02008A

Scherkus, C., Schmidt, S., T. Bornscheuer, U., Gröger, H., Kara, S. & Liese, A. (2017). Kinetic insights into ϵ‐caprolactone synthesis: improvement of an enzymatic cascade reaction. Biotechnology and Bioengineering, 114(6), 1215-1221. https://doi.org/10.1002/bit.26258

Siphamandla Mthetwa, K., Kassier, K., Engel, J., Kara, S., Smit, M. & Opperman, D. J. (2017). Fungal BVMOs as alternatives to cyclohexanone monoxygenase. Enzyme and Microbial Technology, 106, 11-17. https://doi.org/10.1016/j.enzmictec.2017.06.017

2016

Bornadel, A., Hatti-Kaul, R., Hollmann, F. & Kara, S. (2016). Enhancing the productivity of the bi-enzymatic convergent cascade for ɛ-caprolactone synthesis through design of experiments and a biphasic system. Tetrahedron, 72(46), 7222-7228. https://doi.org/10.1016/j.tet.2015.11.054

Engel, J., Opperman, D. J., Hollmann, F. & Kara, S. (2016). Characterisation of a Convergent Enzymatic Cascade for ε-Caprolactone Synthesis. Poster-session præsenteret på 8 th International Congress on Biocatalysis, Hamburg, Slesvig-Holsten, Tyskland.

pesci, L., Kara, S. & Liese, A. (2016). Evaluation of the substrate scope of benzoic acid (de)carboxylases according to chemical and biochemical parameters. ChemBioChem, 17(19), 1845-1850. https://doi.org/10.1002/cbic.201600333

Scherkus, C., Schmidt, S., T. Bornscheuer, U., Gröger, H., Kara, S. & Liese, A. (2016). A fed-batch synthetic strategy for a multi-enzymatic synthesis of Poly‐ϵ‐caprolactone. ChemCatChem, 8(22), 3446-3452. https://doi.org/10.1002/cctc.201600806

2015

Berheide, M., Kara, S. & Liese, A. (2015). Reversibility of asymmetric catalyzed C–C Bond formation by benzoylformate decarboxylase. Catalysis Science & Technology, 5, 2418-2426. https://doi.org/10.1039/C4CY00171K

Bornadel, A., Hatti-Kaul, R., Hollmann, F. & Kara, S. (2015). A bi-enzymatic convergent cascade for ε‐Caprolacton synthesis employing 1,6-hexanediol as a ‘double-smart cosubstrate. ChemCatChem, 7, 2442-2445. https://doi.org/10.1002/cctc.201500511

Kara, S., Schrittwieser, J. H., Gargiulo, S., Ni, Y., Yanase, H., Opperman, D. J. & van Berkel, W. J. H. (2015). Complete enzymatic oxidation of methanol to carbon dioxide: Towards more eco-efficient regeneration systems for reduced nicotinamide cofactors. Advanced Synthesis & Catalysis, 357(8), 1687-1691. https://doi.org/10.1002/adsc.201500173

Zuhse, R., Leggewie, C., Hollmann, F. & Kara, S. (2015). Scaling-up of 'smart cosubstrate' 1,4-butanediol promoted asymmetric reduction of ethyl-4,4,4-trifluoroacetoacetate in organic media. Organic Process Research & Development, 19(2), 369-372. https://doi.org/10.1021/op500374x

2014

Bisagni, S., Summers, B., Kara, S., Hatti-Kaul, R., Grogan, G., Mamo, G. & Hollmann, F. (2014). Exploring the substrate specificity and enantioselectivity of a Baeyer-Villiger monooxygenase from Dietzia sp. D5: oxidation of sulfides and aldehydes. Topics in Catalysis, 57(5), 366-375. https://doi.org/10.1007/s11244-013-0192-1

Hollmann, F. & Kara, S. (2014). Biokatalyse in unkonventionellen Reaktionsmedien. BioSpektrum, 20(1), 100-102. https://doi.org/10.1007/s12268-014-0412-7

Kara, S., Spickermann, D., Weckbecker, A., Leggewie, C., Arends, I. W. C. E. & Hollmann, F. (2014). Bioreductions catalyzed by an alcohol dehydrogenase in non-aqueous media. ChemCatChem, 6, 973-976. https://doi.org/10.1002/cctc.201300841

Kara, S., Schrittwieser, J. H., Hollmann, F. & B. Ansorge-Schumacher, M. (2014). Recent trends and novel concepts in cofactor-dependent biotransformations. Applied Microbiology and Biotechnology, 98(4), 1517-1529. https://doi.org/10.1007/s00253-013-5441-5

Kochius, S., Ni, Y., Kara, S., Gargiulo, S., Schrader, J., Holtmann, D. & Hollmann, F. (2014). Light-accelerated biocatalytic oxidation reactions. ChemPlusChem, 79(11), 1554-1557. https://doi.org/10.1002/cplu.201402152

Petrenz, A., Dominguez De Maria, P., Ramanathan, A., Hanefeld, U., B. Ansorge-Schumacher, M. & Kara, S. (2014). Medium and reaction engineering for the establishment of a chemo-enzymatic dynamic kinetic resolution of rac-benzoin in batch and continuous mode. Journal of Molecular Catalysis B: Enzymatic, 114, 42-49. https://doi.org/10.1016/j.molcatb.2014.10.011

Spickermann, D., Kara, S., Barackov, I., Hollmann, F., Schwaneberg, U., Dünkelmann, P. & Leggewie, C. (2014). Enzyme stabilization by additives under industrial relevant reaction conditions. Journal of Molecular Catalysis B: Enzymatic, 103, 24-28.

2013

Kara, S., Spickermann, D., Schrittwieser, J. H., Weckbecker, A., Leggewie, C., Arends, I. W. C. E. & Hollmann, F. (2013). Access to lactone building blocks via horse liver alcohol dehydrogenase-catalyzed oxidative lactonization. A C S Catalysis, 3(11), 2536-2439. https://doi.org/10.1021/cs400535c

Kara, S., Schrittwieser, J. H. & Hollmann, F. (2013). Strategies for cofactor regeneration in biocatalyzed reductions. I E. Brenna (red.), Synthetic Methods for Biologically Active Molecules: Exploiting the Potential of Bioreductions (s. 209-238). Wiley-VCH Verlag GmbH. https://doi.org/10.1002/9783527665785.ch08

Könst, P., Kara, S., Kochius, S., Holtmann, D., Arends, I. W. C. E., Ludwig, R. & Hollmann, F. (2013). Expanding the scope of laccase-mediator systems. ChemCatChem, 5(10), 3027-3032. https://doi.org/10.1002/cctc.201300205

Schrittwieser, J. H., Coccia, F., Kara, S., Grischek, B., Kroutil, W., dÁlessandro, N. & Hollmann, F. (2013). One-pot combination of enzyme and Pd nanoparticle catalysis for the synthesis of enantiomerically pure 1,2-amino alcohols. Green Chemistry, 15, 3318-3331. https://doi.org/10.1039/C3GC41666F

2012

Kara, S., Spickermann, D., Schrittwieser, J. H., Leggewie, C., van Berkel, W. J. H., Arends, I. W. C. E. & Hollmann, F. (2012). More efficient redox biocatalysis by utilising 1,4-butanediol as a ‘smart cosubstrate’. Green Chemistry and Sustainable Technology, 15, 330-335. https://doi.org/10.1039/C2GC36797A

Könst, P., Merkens, H., Kara, S., Kochius, S., Vogel, A., Zuhse, R., Holtmann, D., Arends, I. W. C. E. & Hollmann, F. (2012). Enantioselective oxidation of aldehydes catalyzed by alcohol dehydrogenase. Angewandte Chemie, 51(48), 9914-9917. https://doi.org/10.1002/anie.201203219

Könst, P., Merkens, H., Kara, S., Kochius, S., Vogel, A., Zuhse, R., Holtmann, D., Arends, I. W. C. E. & Hollmann, F. (2012). Erratum: Enantioselective oxidation of aldehydes catalyzed by alcohol dehydrogenase (Angewandte Chemie - International Edition (2012) 51 (9914-9917) DOI:10.1002/anie.201203219). Angewandte Chemie - International Edition, 51(48), 11924. https://doi.org/10.1002/anie.201208486

2011

Kara, S., Sing Long, W., Berheide, M., Peper, S., Niemeyer, B. & Liese, A. (2011). Influence of reaction conditions on the enantioselectivity of biocatalyzed C–C bond formations under high pressure conditions. Journal of Biotechnology, 152(3), 87-92. https://doi.org/10.1016/j.jbiotec.2011.01.020

Kara, S., J. Mueller, J. & Liese, A. (2011). Online analysis methods for monitoring of bioprocesses. Chimica Oggi-Chemistry Today, 29(2), 38-41. https://www.researchgate.net/publication/234015522_Online_analysis_methods_for_monitoring_of_bioprocesses

Peper, S., Kara, S., Sing Long, W., Liese, A. & Niemeyer, B. (2011). Immobilization and characterization of benzoylformate decarboxylase from Pseudomonas putida on spherical silica. Bioprocess and Biosystems Engineering, 34(6), 671-680. https://doi.org/10.1007/s00449-011-0516-0

2010

Kara, S., Anton, F., Solle, D., Neumann, M., Hitzmann, B., Scheper, T. & Liese, A. (2010). Fluorescence spectroscopy as a novel method for online analysis of biocatalytic C–C bond formations. Journal of Molecular Catalysis B: Enzymatic, 66, 124-129.

Kara, S. & Liese, A. (2010). Enzymatic C–C bond formation, asymmetric. I M. C. Flickinger (red.), Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology. (s. 2034-2049). John Wiley & Sons Inc.. https://doi.org/10.1002/9780470054581.eib272

2009

Berheide, M., Peper, S., Kara, S., Sing Long, W., Schenkel, S., Pohl, M., Niemeyer, B. & Liese, A. (2009). Influence of the hydrostatic pressure and pH on the asymmetric 2‐hydroxyketone formation catalyzed by Pseudomonas putida benzoylformate decarboxylase and variants thereof. Biotechnology and Bioengineering, 106(1), 18-26. https://doi.org/10.1002/bit.22650