Department of Biological and Chemical Engineering

Aarhus University Seal
 Department of Biological and Chemical Engineering Research Key areas in research & development Industrial Biotechnology Research Groups Multiscale Microbial Engineering Publications

Publications

All publications

Sort by: Date
Caspeta, L., Lara, A. R., Pérez, N. O., Flores, N., Bolívar, F. & Ramírez, O. T. (2013). Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies. Journal of Biotechnology, 167(1), 47-55. https://doi.org/10.1016/j.jbiotec.2013.06.001
Fuentes, L. G., Lara, A. R., Martínez, L. M., Ramírez, O. T., Martínez, A., Bolívar, F. & Gosset, G. (2013). Modification of glucose import capacity in Escherichia coli: Physiologic consequences and utility for improving DNA vaccine production. Microbial Cell Factories, 12(1), Article 42. https://doi.org/10.1186/1475-2859-12-42
Borja, G. M., Meza Mora, E., Barrón, B., Gosset, G., Ramírez, O. T. & Lara, A. R. (2012). Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode. Microbial Cell Factories, 11, Article 132. https://doi.org/10.1186/1475-2859-11-132
Pablos, T. E., Soto, R., Mora, E. M., Le Borgne, S., Ramírez, O. T., Gosset, G. & Lara, A. R. (2012). Enhanced production of plasmid DNA by engineered Escherichia coli strains. Journal of Biotechnology, 158(4), 211-214. https://doi.org/10.1016/j.jbiotec.2011.04.015
Lara, A. R. & Ramírez, O. T. (2012). Plasmid DNA production for therapeutic applications. In A. Lorence (Ed.), Recombinant Gene Expression: Reviews and Protocols, Third Edition (pp. 271-303) https://doi.org/10.1007/978-1-61779-433-9_14
Lara, A. R., Knabben, I., Regestein, L., Sassi, J., Caspeta, L., Ramírez, O. T. & Büchs, J. (2011). Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations. Engineering in Life Sciences, 11(4), 382-386. https://doi.org/10.1002/elsc.201000104
Soto, R., Caspeta, L., Barrón, B., Gosset, G., Ramírez, O. T. & Lara, A. R. (2011). High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism. Biochemical Engineering Journal, 56(3), 165-171. https://doi.org/10.1016/j.bej.2011.06.003
Lara, A. R. (2011). Recombinant protein production in escherichia coli. Revista Mexicana de Ingeniera Quimica, 10(2), 209-223.
Pablos, T. E., Mora, E. M., Le Borgne, S., Ramírez, O. T., Gosset, G. & Lara, A. R. (2011). Vitreoscilla hemoglobin expression in engineered Escherichia coli: Improved performance in high cell-density batch cultivations. Biotechnology Journal, 6(8), 993-1002. https://doi.org/10.1002/biot.201000405
Knabben, I., Regestein, L., Marquering, F., Steinbusch, S., Lara, A. R. & Büchs, J. (2010). High cell-density processes in batch mode of a genetically engineered Escherichia coli strain with minimized overflow metabolism using a pressurized bioreactor. Journal of Biotechnology, 150(1), 73-79. https://doi.org/10.1016/j.jbiotec.2010.07.006
Lara, A. R., Taymaz-Nikerel, H., Mashego, M. R., Van Gulik, W. M., Heijnen, J. J., Ramírez, O. T. & Van Winden, W. A. (2009). Fast dynamic response of the fermentative metabolism of Escherichia coli to aerobic and anaerobic glucose pulses. Biotechnology and Bioengineering, 104(6), 1153-1161. https://doi.org/10.1002/bit.22503
Chávez-Béjar, M. I., Lara, A. R., López, H., Hernández-Chávez, G., Martinez, A., Ramírez, O. T., Bolívar, F. & Gosset, G. (2008). Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Applied and Environmental Microbiology, 74(10), 3284-3290. https://doi.org/10.1128/AEM.02456-07
Lara, A. R., Caspeta, L., Gosset, G., Bolívar, F. & Ramírez, O. T. (2008). Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures. Biotechnology and Bioengineering, 99(4), 893-901. https://doi.org/10.1002/bit.21664
Lara, A. R., Vazquez-Limón, C., Gosset, G., Bolívar, F., López-Munguía, A. & Ramírez, O. T. (2006). Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions. Biotechnology and Bioengineering, 94(6), 1164-1175. https://doi.org/10.1002/bit.20954
Lara, A. R., Galindo, E., Ramírez, O. T. & Palomares, L. A. (2006). Living with heterogeneities in bioreactors: Understanding the effects of environmental gradients on cells. Molecular Biotechnology, 34(3), 355-381. https://doi.org/10.1385/MB:34:3:355
De Anda, R., Lara, A. R., Hernández, V., Hernández-Montalvo, V., Gosset, G., Bolívar, F. & Ramírez, O. T. (2006). Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rate. Metabolic Engineering, 8(3), 281-290. https://doi.org/10.1016/j.ymben.2006.01.002
Lara, A. R., Leal, L., Flores, N., Gosset, G., Bolívar, F. & Ramírez, O. T. (2006). Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system. Biotechnology and Bioengineering, 93(2), 372-385. https://doi.org/10.1002/bit.20704

Displaying results 51 to 67 out of 67

Previous

1

2

Revised 16.01.2025