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Department of Biological and Chemical Engineering

Publications by Medical Biotechnology

Are you looking for publications by Section of Medical Biotechnology? On this page you can find all the publications made by the Section of Medical Biotechnology - Department of Biological & Chemical Engineering, Aarhus University.

Below you can find a list of all the publications, their publishing date, their author(s), and titles. The list can be sorted by date, author, and title:

List of Publications

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Van Vaerenbergh, M., de Smet, L., Rafei-Shamsabadi, D., Blank, S., Spillner, E., Ebo, D., Devreese, B., Jakob, T. & C. de Graaf, D. (2015). IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology. Molecular Immunology, 63(2), 449-455. https://doi.org/10.1016/j.molimm.2014.09.018

Jakob, T., Spillner, E. & Lamers, M. (2016). IgE als Zielstruktur für therapeutische Intervention. In T. Biedermann, H. Renz, W. Heppt & M. Röcken (Eds.), Allergologie (pp. 631-640). Springer. https://doi.org/10.1007/978-3-642-37203-2_58

Blank, S., Seismann, H., Bockisch, B., Rühl, D., Bredehorst, R., Braren, I., Grunwald, T., Cifuentes, L., McIntyre, M., Ring, J., Ollert, M. W. & Spillner, E. (2010). Identification, recombinant expression, and characterization of the 100 kDa high molecular weight hymenoptera venom allergens Api m 5 and Ves v 3. Journal of Immunology, 184(9), 5403-5413. https://doi.org/10.4049/jimmunol.0803709

Cifuentes, L., Vosseler, S., Blank, S., Seismann, H., Grunwald, T., Darsow, U., Bredehorst, R., Mempel, M., Spillner, E., Ring, J. & Ollert, M. (2014). Identification of hymenoptera venom-allergic patients with negative specific IgE to venom extract by using recombinant allergens. Journal of Allergy and Clinical Immunology, 133(3), 909-910.

Munir, S., Figueroa, R. J., Koch, T. G., Le, D. Q. S., Nygaard, J. V., Søballe, K. & Ulrich-Vinther, M. (2011). Hypoxia Enhances Chondrogenic Differentiation of Human Cord Blood Multilineage Progenitor Cells Seeded on a Novel Scaffold of Freeze Dried Polycaprolactone. Abstract from DOS årsmøde, København, Denmark.

Spillner, E., Blank, S. & Jakob, T. (2014). Hymenoptera allergens: from venom to ”venome”. Frontiers in Immunology, 5(77). https://doi.org/10.3389/fimmu.2014.00077

Jensen, T. H. L., Jakobsen, T., Baas, J., Nygaard, J. V., Dolatshahi-Pirouz, A., Hovgaard, M. B., Foss, M., Bünger, C., Besenbacher, F. & Søballe, K. (2010). Hydroxyapatite nanoparticles in poly-D,L-lactic acid coatings on porous titanium implants conducts bone formation. Journal of Biomedical Materials Research. Part A. https://doi.org/10.1002/jbm.a.32863

Offermann, N., Plum, M., Hübner, U., Rathloff, K., Braren, I., Fooke, M. & Spillner, E. (2016). Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains. Allergy: European Journal of Allergy and Clinical Immunology, 71(12), 1794-1799. https://doi.org/10.1111/all.13038

Bantleon, F., Wolf, S., Seismann, H., Dam, S. S., Lorentzen, A., Miehe, M., Jabs, F., Jakob, T., Plum, M. & Spillner, E. (2016). Human IgE is efficiently produced in glycosylated and biologically active form in lepidopteran cells. Molecular Immunology, 72, 49-56. https://doi.org/10.1016/j.molimm.2016.02.013

Kjeldsen, C. R., Stenderup, K., Clausen, J. T., Hasselager, E. & Dam, T. N. (2007). How is Keratinocyte Proliferation Induced by Interleukin 20? In Ikke angivet (Vol. 127, pp. 340). J Invest Dermatol.

Rosada, C., Stenderup, K., Clausen, J. T., Hasselager, E. & Dam, T. N. (2007). How is keratinocyte proliferation induced by Interleukin 20?. Abstract from 37th Annual Meeting of the European Society for Dermatological Research, Zurich, Switzerland.

Xu, R., Taskin, M. B., Rubert, M., Seliktar, D., Besenbacher, F. & Chen, M. (2015). hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold. Scientific Reports, 5, 1-7. Article 8480. https://doi.org/10.1038/srep08480

Wang, Y., Su, Y., Zhang, Y. & Chen, M. (2022). High-Voltage Wave Induced a Unique Structured Percolation Network with a Negative Gauge Factor. ACS applied materials & interfaces, 14(4), 5661-5672. https://doi.org/10.1021/acsami.1c23741

Münster, J., Ziegelmüller, P., Spillner, E. & Bredehorst, R. (2006). High level expression of monomeric and dimeric human alpha1,3-fucosyltransferase V. Journal of Biotechnology, 121(4), 448-57. https://doi.org/10.1016/j.jbiotec.2005.08.015

Kamp, S., Fiehn, A. M., Stenderup, K., Rosada, C., Pakkenberg, B., Kemp, K., Dam, T. N. & Jemec, G. (2011). Hidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume is significantly reduced in uninvolved hair follicles from patients with Hidradenitis Suppurativa. British Journal of Dermatology, 164(5), 1017-22. https://doi.org/10.1111/j.1365-2133.2011.10224.x

Xu, R., Gao, J., Cao, C., Shi, M., Zhang, Y., Hong, S., Guo, S., Chen, M., Song, P., Fu, G., Li, J., Liang, T., Miao, Y., Tang, L., Yang, J., Li, N. & Dong, M. (2023). HDL mimetics protect Alzheimer's patients carrying APOE ε4 from SARS-CoV-2 invasion. Nano Today, 53, Article 102051. https://doi.org/10.1016/j.nantod.2023.102051

Hall, J. P., Gurung, S. P., Henle, J., Poidl, P., Andersson, J., Lincoln, P., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. & Cardin, C. J. (2017). Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects. Chemistry: A European Journal, 23(21), 4981-4985. https://doi.org/10.1002/chem.201605508

Kristensen, S. K., Salamone, S., Rasmussen, M. R., Marqvorsen, M. H. S. & Jensen, H. H. (2016). Glycosyl ortho-Methoxybenzoates: Catalytically Activated Glycosyl Donors with an Easily Removable and Recyclable Leaving Group. European Journal of Organic Chemistry, 2016(32), 5365-5376. https://doi.org/10.1002/ejoc.201600747

Braren, I., Blank, S., Seismann, H., Deckers, S., Ollert, M., Grunwald, T. & Spillner, E. (2007). Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries. Clinical Chemistry, 53(5), 837-44. https://doi.org/10.1373/clinchem.2006.078360

Singer, J., Fazekas, J., Wang, W., Weichselbaumer, M., Matz, M., Mader, A., Steinfellner, W., Meitz, S., Mechticheriakova, D., Sobanov, J., Willmann, M., Stockner, T., Spillner, E., Kunert, R. & Jensen-Jarolim, E. (2014). Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients. Molecular Cancer Therapeutics, 13(7), 1777-1790. https://doi.org/10.1158/1535-7163.MCT-13-0288

Kölln, J., Matzas, M., Jänner, N., Mix, T., Klensang, K., Bredehorst, R. & Spillner, E. (2004). Functional analysis of Cobra Venom Factor/human C3 chimeras transiently expressed in mammalian cells. Molecular Immunology, 41(1), 19-28. https://doi.org/10.1016/j.molimm.2004.02.003

Noor, M. A., Nygaard, J. V., Johansen, P. & Hasenkam, J. M. (2018). Frequency Dependant Viscoelastic Properties of different Regions of Aorta. Poster session presented at 36th Annual Meeting. Danish Society for Biomedical Engineering, Vingsted, Denmark.

Kötzler, M. P., Blank, S., Behnken, H. N., Alpers, D., Bantleon, F. I., Spillner, E. & Meyer, B. (2012). Formation of the immunogenic α1,3-fucose epitope: elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. Insect Biochemistry and Molecular Biology, 42(2), 116-25. https://doi.org/10.1016/j.ibmb.2011.11.004

Xu, R., Dagnæs-Hansen, F., Bach, L. W., Axelsen, S. M., Seliktar, D. & Chen, M. (2018). Fibrogenic and angiogenic commitments of human induced pluripotent stem cells derived mesenchymal stem cells in connective tissue growth factor-delivering scaffold in an immune-deficient mice model. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 106(6), 2266-2274. https://doi.org/10.1002/jbm.b.34030

Nygaard, J. V. (2005). Femlab Analysis of Open Aluminium Foam in Compression. In Proceedings of the COMSOL Multiphysics User's Conference 2005

Liljenhjerte, J., Vudayagiri, S., von Solms, N. & Nygaard, J. V. (2023). Feasibility of periodic stabilizers for extending coiled tubing reach. Geoenergy Science and Engineering, 227, Article 211779. https://doi.org/10.1016/j.geoen.2023.211779

Sørensen, T. L.-M., Dupont, Y., Vilsen, B. & Andersen, J. P. (2000). Fast kinetic analysis of conformational changes in mutants of the Ca²⁺-ATPase of sarcoplasmic reticulum. Journal of Biological Chemistry, 275, 5400-5408. https://doi.org/10.1074/jbc.275.8.5400

Jiang, Z., Xia, D., Li, Y., Li, J., Li, Q., Chen, M., Huang, Y., Besenbacher, F. & Dong, M. (2013). Facilitating the mechanical properties of a high-performance pH-sensitive membrane by cross-linking graphene oxide and polyacrylic acid. Nanotechnology, 24(33), 335704. https://doi.org/10.1088/0957-4484/24/33/335704

Chen, M., Le, D. Q. S., Hein, S., Li, P., Nygaard, J. V., Kassem, M., Kjems, J., Besenbacher, F. & Bünger, C. (2012). Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release. International Journal of Nanomedicine (Online), (7), 4285-97. https://doi.org/10.2147/IJN.S33083

Aagaard, J. B., Fischer, M., Lober, J., Bolbro Neumann, F., Allahverdi, D., Sivelle, C., Miehe, M. & Spillner, E. (2023). Extract-shaped immune repertoires as source for nanobody-based human IgE in grass pollen allergy. Molecular Biotechnology, 65, 1518-1527. https://doi.org/10.1007/s12033-023-00664-8

Van Vaerenbergh, M., Cardoen, D., M. Formesyn, E., Brunain, M., Van Driessche, G., Blank, S., Spillner, E., Verleyen, P., Wenseleers, T., Schoofs, L., Devreese, B. & C. de Graaf, D. (2013). Extending the honeybee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. Insect Molecular Biology, 22(2), 199-210.

Rottboell, L., de Foenss, S., Thomsen, K., Christiansen, H., Andersen, S. M., Dam, T. N., Kjeldsen, C. R. & Stenderup, K. (2015). Exploring valrubicin’s effect on Propionibacterium acnes-induced skin inflammation in vitro and in vivo. Dermatology Reports, 7/3. https://doi.org/10.4081/dr.2015.6246

Friis, S. J., Strøm Hansen, T., Olesen, C. G., Poulsen, M., Gregersen, H. & Nygaard, J. V. (2025). Experimental and numerical study of solid needle insertions into human stomach tissue. Journal of the Mechanical Behavior of Biomedical Materials, 162, Article 106832. https://doi.org/10.1016/j.jmbbm.2024.106832

Friis, S. J., Nygaard, J. V., Poulsen, M., Strøm Hansen, T. & Herskind, P. (2021). Examination of Porcine Gastric Biomechanics in the Antrum Region. International Journal of Biomedical and Biological Engineering, 15(10). https://publications.waset.org/abstracts/134807/pdf

Liljenhjerte, J. & Nygaard, J. V. (2021). Evaluating stabilizing initiatives to extend coiled tubing reach. Journal of Petroleum Science and Engineering, 205, Article 108905. https://doi.org/10.1016/j.petrol.2021.108905

Deckers, S., Braren, I., Greunke, K., Meyer, N., Rühl, D., Bredehorst, R. & Spillner, E. (2009). Establishment of hapten-specific monoclonal avian IgY by conversion of antibody fragments obtained from combinatorial libraries. Biotechnology and Applied Biochemistry, 52(Pt 1), 79-87. https://doi.org/10.1042/BA20080032

Huang, S., Hong, S., Su, Y., Jiang, Y., Fukushima, S., Gill, T. M., Yilmaz, N., Tiwari, S., Nomura, K., Kalia, R., Nakano, A., Shimojo, F., Vashishta, P., Chen, M. & Zheng, X. (2020). Enhancing combustion performance of nano-Al/PVDF composites with β-PVDF. Combustion and Flame, 219, 467-477. https://doi.org/10.1016/j.combustflame.2020.06.011

Wang, J., Zhang, Z., Zhang, H., Li, C., Chen, M., Liu, L. & Dong, M. (2019). Enhanced Photoresponsive Graphene Oxide-Modified g-C ₃ N ₄ for Disassembly of Amyloid β Fibrils. ACS Applied Materials & Interfaces, 11(1), 96-103. https://doi.org/10.1021/acsami.8b10343

Song, J., Kahveci, D., Chen, M., Guo, Z., Xie, E., Xu, X., Besenbacher, F. & Dong, M. (2012). Enhanced Catalytic Activity of Lipase Encapsulated in PCL Nanofibers. Langmuir, 28. https://doi.org/10.1021/la300469s

Sarikhani, E., Meganathan, D. P., Larsen, A. K. K., Rahmani, K., Tsai, C. T., Lu, C. H., Marquez-Serrano, A., Sadr, L., Li, X., Dong, M., Santoro, F., Cui, B., Klausen, L. H. & Jahed, Z. (2024). Engineering the Cellular Microenvironment: Integrating Three-Dimensional Nontopographical and Two-Dimensional Biochemical Cues for Precise Control of Cellular Behavior. ACS Nano, 18(29), 19064-19076. https://doi.org/10.1021/acsnano.4c03743

Kölln, J., Bredehorst, R. & Spillner, E. (2005). Engineering of human complement component C3 for catalytic inhibition of complement. Immunology Letters, 98(1), 49-56. https://doi.org/10.1016/j.imlet.2004.10.010

Kang, R., Svend Le, D. Q., Li, H., Lysdahl, H., Chen, M., Besenbacher, F. & Bünger, C. (2013). Engineered three-dimensional nanofibrous multi-lamellar structure for annulus fibrosus repair. Journal of Materials Chemistry B, 1(40), 5462-5468. https://doi.org/10.1039/c3tb20562b, https://doi.org/10.1039/c3tb20562b

Taskin, M. B., Klausen, L. H., Dong, MD. & Chen, M. (2020). Emerging wet electrohydrodynamic approaches for versatile bioactive 3D interfaces. Nano Research, 13(2), 315-327. https://doi.org/10.1007/s12274-020-2635-x

Toftdal, M. S., Grunnet, L. G. & Chen, M. (2024). Emerging Strategies for Beta Cell Encapsulation for Type 1 Diabetes Therapy. Advanced Healthcare Materials, 13(19), Article 2400185. https://doi.org/10.1002/adhm.202400185

Anand, S., Müller, C. A., Nørrehvedde Jensen, B. & Chen, M. (2024). Embracing Remote Fields as the Fourth Dimension of Tissue Biofabrication. Advanced Functional Materials, 34(32), Article 2401654. https://doi.org/10.1002/adfm.202401654

Frydenlund, A., Poggi, A. I., Hansen, S. K., Brage-Andersen, M., Merhi, Y., Agarwala, S., Mikkelsen, P. H., Nygaard, J. V., Steffensen, I. E. & Suetta, C. (2021). Elektrisk stimulation mod muskel- og funktionstab hos en patient indlagt med COVID-19. Ugeskrift for Læger, 183(20), 1-4. Article V03210275. https://ugeskriftet.dk/files/scientific_article_files/2021-05/v03210275_web.pdf

Chen, M., Nielsen, S. R., Uyar, T., Zhang, S., Zafar, A., Dong, M. & Besenbacher, F. (2013). Electrospun UV-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex. Journal of Materials Chemistry, Part C(1), 850-855. https://doi.org/10.1039/c2tc00180b

Femenias, M. R., Dehli, J., Li, Y., Taskin, M. B., Xu, R., Besenbacher, F. & Chen, M. (2014). Electrospun PCL/PEO Coaxial Fibers for basic Fibroblast Growth Factor Delivery. Journal of Materials Chemistry B, 2(48), 8538-8546. https://doi.org/10.1039/C4TB01258E

Keshvardoostchokami, M., Majidi, S. S., Huo, P., Ramachandran, R., Chen, M. & Liu, B. (2021). Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering. Nanomaterials, 11(1), 1-23. Article 21. https://doi.org/10.3390/nano11010021

Chen, M., Li, Y. & Besenbacher, F. (2014). Electrospun nanofibers-mediated on-demand drug release. Advanced Healthcare Materials, 3(11), 1721-1732. https://doi.org/10.1002/adhm.201400166

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