Publications by Medical Biotechnology

Are you looking for publications by Section of Medical Biotechnology? On this page you can find all the publications made by the Section of Medical Biotechnology - Department of Biological & Chemical Engineering, Aarhus University.

Below you can find a list of all the publications, their publishing date, their author(s), and titles. The list can be sorted by date, author, and title:

List of Publications

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Justesen, J., Stenderup, K., Ebbesen, E., Mosekilde, L., Steiniche, T. & Kassem, M. (2001). Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology, 2, 165-171.

Justesen, J., Stenderup, K., Eriksen, E. F. & Kassem, M. (2002). Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures. Calcif. Tissue Int., 71(1), 36-44.

Justesen, J., Stenderup, K. & Kassem, M. (2001). Mesenchymal stem cells. Potential use in cell and gene therapy of bone loss caused by aging and osteoporosis. Ugeskrift for Laeger, 163, 5491-5495.

Justesen, J., Mosekilde, L., Holmes, M., Stenderup, K., Gasser, J., Mullins, J. J., Seckl, J. R. & Kassem, M. (2004). Mice deficient in 11beta-hydroxysteroid dehydrogenase type 1 lack bone marrow adipocytes, but maintain normal bone formation. Endokrinologiya, 145, 1916-1925.

Justesen, J., Pedersen, S. B., Stenderup, K. & Kassem, M. (2004). Subcutaneous adipocytes can differentiate into bone-forming cells in vitro and in vivo. Tissue Engineering. Part C. Methods, 10(3-4), 381-91. https://doi.org/10.1089/107632704323061744

Jiang, Z., Li, Q., Chen, M., Li, J., Li, J., Huang, Y., Besenbacher, F. & Dong, M. (2013). Mechanical reinforcement fibers produced by gel-spinning of poly-acrylic acid (PAA) and graphene oxide (GO) composites. Nanoscale, 5(14), 6265-6269. https://doi.org/10.1039/c3nr00288h

Jiang, Z., Xia, D., Li, Y., Li, J., Li, Q., Chen, M., Huang, Y., Besenbacher, F. & Dong, M. (2013). Facilitating the mechanical properties of a high-performance pH-sensitive membrane by cross-linking graphene oxide and polyacrylic acid. Nanotechnology, 24(33), 335704. https://doi.org/10.1088/0957-4484/24/33/335704

Jiang, Z., Li, J., Aslan, H., Li, Q., Li, Y., Chen, M., Huang, Y., Froning, J. P., Otyepka, M., Zbořil, R., Besenbacher, F. & Dong, MD. (2014). A high eﬃciency H₂S gas sensor material: paper like Fe₂O₃/graphene nanosheets and structural alignment dependency of device eﬃciency. Journal of Materials Chemistry A, 2, 6714–6717. https://doi.org/10.1039/c3ta15180h

Jiang, X., Li, Y., Liu, Y., Chen, C. & Chen, M. (2016). Selective enhancement of human stem cell proliferation by mussel inspired surface coating. RSC Advances, 65(6), 60206 – 60214. https://doi.org/10.1039/C6RA11173D

Jensen-Jarolim, E., Bax, HJ., Bianchini, R., Capron, M., Corrigan, C., Castells, M., Dombrovicz, D., Daniels-Wells, HR., Fazekas, J., Fiebiger, E., Gatault, S., Gould, H., Janda, J., Josephs, DH., Karagiannis, P., Levi-Schaffer, F., Meshcheryakova, A., Mechtcheriakova, D., Mekori, Y. ... Karagiannis, S. N. (2017). AllergoOncology - the Impact of Allergy in Oncology. EAACI Position Paper. Allergy: European Journal of Allergy and Clinical Immunology, 72(6), 866-887. https://doi.org/10.1111/all.13119

Jensen, A-M. L., Sørensen, T. L-M., Olesen, C., Møller, J. V. & Nissen, P. (2006). Modulatory and catalytic modes of ATP binding by the calcium pump. E M B O Journal, 25(11), 2305-2314.

Jensen, T. H. L., Jakobsen, T., Baas, J., Nygaard, J. V., Dolatshahi-Pirouz, A., Hovgaard, M. B., Foss, M., Bünger, C., Besenbacher, F. & Søballe, K. (2010). Hydroxyapatite nanoparticles in poly-D,L-lactic acid coatings on porous titanium implants conducts bone formation. Journal of Biomedical Materials Research. Part A. https://doi.org/10.1002/jbm.a.32863

Jensen, T. H. L., Baas, J., Dolatshahi-Pirouz, A., Jacobsen, T., Singh, G., Nygaard, J. V., Foss, M., Bechtold, J., Bünger, C., Besenbacher, F. & Søballe, K. (2011). Osteopontin functionalization of hydroxyapatite nanoparticles in a PDLLA matrix promotes bone formation. Journal of Biomedical Materials Research. Part A, 99(1), 94-101. https://doi.org/10.1002/jbm.a.33166

Jensen, J., Rölfing, J. H. D., Svend Le, D. Q., Kristiansen, A. A., Nygaard, J. V., Hokland, L. B., Bendtsen, M., Kassem, M., Lysdahl, H. & Bünger, C. (2014). Surface-modified functionalized polycaprolactone scaffolds for bone repair: In vitro and in vivo experiments. Journal of Biomedical Materials Research. Part A, 102(9), 2993-3003. https://doi.org/10.1002/jbm.a.34970

Jensen, R. K., Plum, M., Tjerrild, L., Jakob, T., Spillner, E. & Andersen, G. R. (2015). Structure of the omalizumab Fab. Acta Crystallographica Section F: Structural Biology Communications, 71(Pt 4), 419-426. https://doi.org/10.1107/S2053230X15004100

Jensen, R. K., Jabs, F., Miehe, M., Mølgaard, B., Pfützner, W., Möbs, C., Spillner, E. & Andersen, G. R. (2020). Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy. Allergy: European Journal of Allergy and Clinical Immunology, 75(8). https://doi.org/10.1111/all.14222

Jakobsen, M., Stenderup, K., Rosada, C., Moldt, B., Kamp, S., Dam, T. N., Jensen, T. G. & Mikkelsen, J. G. (2008). Partial Correction of Psoriasis upon Genetic Knock-Down of Human TNF-α by Lentivirus-Encoded shRNAs in a Xenograft Mouse Model. Abstract from American Society of Gene Therapy, Boston, Massachusetts, United States.

Jakobsen, M., Stenderup, K., Rosada, C., Moldt, B., Kamp, S., Dam, T. N., Jensen, T. G. & Mikkelsen, J. G. (2009). Amelioration of Psoriasis by Anti-TNF-alpha RNAi in the Xenograft Transplantation Model. Molecular Therapy. https://doi.org/10.1038/mt.2009.141

Jakobsen, M., Askou, A. L., Stenderup, K., Rosada, C., Dagnæs-Hansen, F., Jensen, T. G., Corydon, T. J., Mikkelsen, J. G. & Aagaard, L. (2015). Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin. Human Gene Therapy. Methods, 26(4), 123-33. https://doi.org/10.1089/hgtb.2014.135

Jakobsen, M. V., Askou, A. L., Dokkedahl, K. S., Kjeldsen, C. R., Dagnæs-Hansen, F., Jensen, T. G., Corydon, T. J., Mikkelsen, J. G. & Aagaard, L. (2015). Efficient in vivo gene transfer to xenotransplanted human skin by lentivirus-mediated, but not by AAV-directed, gene delivery. Poster session presented at Annual Congress The European Society of Gene and Cell Therapy (ESGCT), Helsinki, Finland.

Jakob, T., Blank, S., Spillner, E. & Ollert, M. (2011). Rekombinante Insektengift-Allergene: Ist das Bienen- oder doch das Wespengift schuld? Der Deutsche Dermatologe, 59, 759-761.

Jakob, T., Köhler, J., Blank, S., Spillner, E., Magnusson, U., Lidholm, J. & Huss-Marp, J. (2012). Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant-negative patients with bee venom allergy. Journal of Allergy and Clinical Immunology, 130(1), 276-278. https://doi.org/10.1016/j.jaci.2012.03.048

Jakob, T., Spillner, E. & Lamers, M. (2016). IgE als Zielstruktur für therapeutische Intervention. In T. Biedermann, H. Renz, W. Heppt & M. Röcken (Eds.), Allergologie (pp. 631-640). Springer. https://doi.org/10.1007/978-3-642-37203-2_58

Jakob, T., Blank, S. & Spillner, E. (2015). Optimierte Diagnostik der Insektengiftallergie durch rekombinante Allergene. In J. Kleine-Tebbe & T. Jakob (Eds.), Molekulare Allergiediagnostik (pp. 257-275). Springer. https://doi.org/10.1007/978-3-662-45221-9_16

Jakob, T., Müller, S., Rafei-Shamsabadi, D., Bantleon, F. & Spillner, E. (2014). Aktueller Stand und neue Entwicklungen in der Diagnostik mit rekombinanten Insektengiftallergenen. Allergologie, 37(9), 352-361.

Jakob, T., Blank, S. & Spillner, E. (2017). Benefits and limitations of recombinant allergens in diagnostics of insect venom allergy. In J. Kleine-Tebbe & T. Jakob (Eds.), Molecular Allergy Diagnostics (pp. 341-362). Springer. https://doi.org/10.1007/978-3-319-42499-6_18

Jakob, T., Rafei-Shamsabadi, D., Spillner, E. & Müller, S. (2017). Diagnostics in hymenoptera venom allergy: Current concepts and developments with special focus on molecular allergy diagnostics. Allergo Journal International, 26(3), 93-105. https://doi.org/10.1007/s40629-017-0014-2

Jakob, T. & Spillner, E. (2017). Comparing sensitivity of Hymenoptera allergen components on different diagnostic assay systems: Comparing apples and oranges. Journal of Allergy and Clinical Immunology, 139(3), 1066-1067. https://doi.org/10.1016/j.jaci.2016.09.058

Jakob, T., Müller, U., Helbling, A. & Spillner, E. (2017). Component resolved diagnostics for Hymenoptera venom allergy. Current Opinion in Allergy and Clinical Immunology, 17(5), 363-372. https://doi.org/10.1097/ACI.0000000000000390

Jakob, T., Rauber, M. M., Perez-Riverol, A., Spillner, E. & Blank, S. (2020). The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy. Current Allergy and Asthma Reports, 20(9), [48]. https://doi.org/10.1007/s11882-020-00943-3

Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., Mandolesi, M., Rauber, M. M., Pfützner, W., Jakob, T., Möbs, C., Andersen, G. R. & Spillner, E. (2018). Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. Nature Communications, 9(1), [7]. https://doi.org/10.1038/s41467-017-02312-7

Islamagič, L., Tjørnild, M. J., Carlson Hanse, L., Nygaard, J. V. & Hasenkam, J. M. (2023). Biomechanical comparison of porcine mitral leaflets with porcine small intestinal submucosa extracellular matrix. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 237(4), 435 - 442. https://doi.org/10.1177/09544119231158248

Islamagic, L., Tjørnild, M. J., Carlson Hanse, L., Nygaard, J. V. & Hasenkam, J. M. (2019). Biomechanical properties of porcine small intestinal submucosa matrix compared with porcine mitral valve leaflets. Poster session presented at 29th Annual Meeting SSRCTS, Geilo, Norway.

Huang, S., Hong, S., Su, Y., Jiang, Y., Fukushima, S., Gill, T. M., Yilmaz, N., Tiwari, S., Nomura, K., Kalia, R., Nakano, A., Shimojo, F., Vashishta, P., Chen, M. & Zheng, X. (2020). Enhancing combustion performance of nano-Al/PVDF composites with β-PVDF. Combustion and Flame, 219, 467-477. https://doi.org/10.1016/j.combustflame.2020.06.011

Hoof, I., Schulten, V., Layhadi, J. A., Stranzl, T., Christensen, L. H., Herrera de la Mata, S., Seumois, G., Vijayanand, P., Lundegaard, C., Niss, K., Lund, A., Ahrenfeldt, J., Holm, J., Steveling, E., Sharif, H., Durham, S. R., Peters, B., Shamji, M. H. & Andersen, P. S. (2020). Allergen-specific IgG⁺ memory B cells are temporally linked to IgE memory responses. The Journal of allergy and clinical immunology, 146(1), 180-191. https://doi.org/10.1016/j.jaci.2019.11.046

Hofmann, S. C., Pfender, N., Weckesser, S., Jakob, T., Blank, S., Spillner, E. & Huss-Marp, J. (2011). Reply. Journal of Allergy and Clinical Immunology, 128(1), 248. https://doi.org/10.1016/j.jaci.2011.02.020

Hjorth-Jensen, S. J., Oksanen, E., Nissen, P. & Sørensen, T. L. M. (2020). Prospects for membrane protein crystals in NMX. In P. C. E. Moody (Ed.), Neutron Crystallography in Structural Biology (pp. 47-68). Elsevier. Methods in Enzymology Vol. 634 https://doi.org/10.1016/bs.mie.2019.11.019

Hayes, S., White, T., Boote, C., Kamma-Lorger, C. S., Bell, J., Sorenson, T., Terrill, N., Shebanova, O. & Meek, K. M. (2017). The structural response of the cornea to changes in stromal hydration. Journal of the Royal Society. Interface, 14(131). https://doi.org/10.1098/rsif.2017.0062

Hayes, S., Lewis, P., Islam, M. M., Doutch, J., Sorensen, T., White, T., Griffith, M. & Meek, K. M. (2015). The structural and optical properties of type III human collagen biosynthetic corneal substitutes. Acta Biomaterialia, 25, 121-30. https://doi.org/10.1016/j.actbio.2015.07.009

Hayes, S., Khan, S., Boote, C., Kamma-Lorger, C. S., Dooley, E., Lewis, J., Hawksworth, N., Sorensen, T., Daya, S. & Meek, K. M. (2012). Depth profile study of abnormal collagen orientation in keratoconus corneas. JAMA Ophthalmology, 130(2), 251-2. https://doi.org/10.1001/archopthalmol.2011.1467

Hauge, E., Christiansen, H., Rosada, C., de Darkó, E., Dam, T. N. & Stenderup, K. (2012). Topical valrubicin application reduces skin inflammation in murine models. British Journal of Dermatology, 167(2), 288-95. https://doi.org/10.1111/j.1365-2133.2012.10964.x

Haslund, D., Ryø, L. B., Majidi, S. S., Christiansen, I. R., Skipper, K. A., Fryland, T., Bohn, A. B., Koch, C., Thomsen, M. K., Palarasah, Y., Corydon, T. J., Bygum, A., Nejsum, L. N. & Mikkelsen, J. G. (2019). Dominant negative SERPING1 variants cause intracellular retention of C1-inhibitor in hereditary angioedema. Journal of Clinical Investigation, 129(1), 388-405. [CI98869]. https://doi.org/10.1172/JCI98869

Harkness, L., Mahmood, A., Ditzel, N., Abdallah, BM., Nygaard, J. V. & Kassem, M. (2011). Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential. The Bone, 48(2), 231-241.

Hansen, S. G., Taskin, M. B., Chen, M., Wogensen, L., Vinge Nygaard, J. & Axelsen, S. M. (2020). Electrospun nanofiber mesh with fibroblast growth factor and stem cells for pelvic floor repair. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 108(1), 48-55. https://doi.org/10.1002/jbm.b.34364

Hall, J. P., Gurung, S. P., Henle, J., Poidl, P., Andersson, J., Lincoln, P., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. & Cardin, C. J. (2017). Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects. Chemistry: A European Journal, 23(21), 4981-4985. https://doi.org/10.1002/chem.201605508

Hall, J. P., Keane, P. M., Beer, H., Buchner, K., Winter, G., Sorensen, T. L., Cardin, D. J., Brazier, J. A. & Cardin, C. J. (2016). Delta chirality ruthenium 'light-switch' complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research, 44(19), 9472-9482. https://doi.org/10.1093/nar/gkw753

Grunwald, T., Bockisch, B., Spillner, E., Bredehorst, R., Ring, J. & Ollert, M. W. (2006). Molecular cloning and expression in insect cells of honeybee venom allergen acid phosphatase (Api m 3). Journal of Allergy and Clinical Immunology, 117(4), 848-854. https://doi.org/10.1016/j.jaci.2005.12.1331

Gross-Petersen, J., Nygaard, J. V. & Skov, A. L. (2017). Innovative Pipeline Concepts for North Sea Applications. Poster session presented at Danish Hydrocarbon Research and Technology Centre Technology Conference 2017, Kolding, Denmark. http://orbit.dtu.dk/ws/files/163303320/Pages_from_DHRTC_Poster_abstracts_2017_at_registrere_30.pdf

Greunke, K., Braren, I., Alpers, I., Blank, S., Sodenkamp, J., Bredehorst, R. & Spillner, E. (2008). Recombinant IgY for improvement of immunoglobulin-based analytical applications. Clinical Biochemistry, 41(14-15), 1237-44. https://doi.org/10.1016/j.clinbiochem.2008.07.004

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Revised 21.11.2022

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