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Department of Biological and Chemical Engineering

Publications by Medical Biotechnology

Are you looking for publications by Section of Medical Biotechnology? On this page you can find all the publications made by the Section of Medical Biotechnology - Department of Biological & Chemical Engineering, Aarhus University.

Below you can find a list of all the publications, their publishing date, their author(s), and titles. The list can be sorted by date, author, and title:

List of Publications

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Jakob, T. & Spillner, E. (2017). Comparing sensitivity of Hymenoptera allergen components on different diagnostic assay systems: Comparing apples and oranges. Journal of Allergy and Clinical Immunology, 139(3), 1066-1067. https://doi.org/10.1016/j.jaci.2016.09.058

Jakob, T., Rafei-Shamsabadi, D., Spillner, E. & Müller, S. (2017). Diagnostics in hymenoptera venom allergy: Current concepts and developments with special focus on molecular allergy diagnostics. Allergo Journal International, 26(3), 93-105. https://doi.org/10.1007/s40629-017-0014-2

Jiang, X., Li, Y., Liu, Y., Chen, C. & Chen, M. (2016). Selective enhancement of human stem cell proliferation by mussel inspired surface coating. RSC Advances, 65(6), 60206 – 60214. https://doi.org/10.1039/C6RA11173D

Xu, R., Taskin, M. B., Dagnæs-Hansen, F., Meyer, T., Bach, L. W., Axelsen, S. M., Besenbacher, F. & Chen, M. (2015). Application of a Novel 3D Biofunctional Scaffold for hiPS-MSC Fibrogenesis. Abstract from 2015 4th TERMIS World Congress , Boston, United States. http://online.liebertpub.com/toc/tea/21/S1

Kelly, C. L., Liu, Z., Yoshihara, A., Jenkinson, S. F., Wormald, M. R., Otero, J. M., Estévez, A. M., Kato, A., Marqvorsen, M. H. S., Fleet, G. W. J., Estevez, R. J., Izumori, K. & Heap, J. T. (2016). Synthetic chemical inducers and genetic decoupling enable orthogonal control of the rhaBAD promoter. A C S Synthetic Biology, 1136-1145. https://doi.org/10.1021/acssynbio.6b00030

Li, Y., Slemming-Adamsen, P., Wang, J., Song, J., Wang, X., Yu, Y., Dong, MD., Chen, C., Besenbacher, F. & Chen, M. (2017). Light responsive hybrid nanofibres for on-demandtherapeutic drug and cell delivery. Journal of Tissue Engineering and Regenerative Medicine, 11(8), 2411–2420. https://doi.org/10.1002/term.2169

Tian, L., Prabhakaran, M., Hu, J., Chen, M., Besenbacher, F. & Ramakrishnaa , S. (2016). Synergistic effect of topography, surface chemistry and conductivity of the electrospun nanofibrous scaffold on cellular response of PC12 cells. Colloids and Surfaces B: Biointerfaces, 145, 420-429. https://doi.org/10.1016/j.colsurfb.2016.05.032

Offermann, N., Plum, M., Hübner, U., Rathloff, K., Braren, I., Fooke, M. & Spillner, E. (2016). Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains. Allergy: European Journal of Allergy and Clinical Immunology, 71(12), 1794-1799. https://doi.org/10.1111/all.13038

Stjernholm, T., Andersen, P. O., Nielsen, A. L-L., Johansen, C., Iversen, L., Kjeldsen, C. R. & Stenderup, K. (2017). Leptin-deficiency in ob/ob mice counteracts imiquimod (IMQ)-induced psoriasis-like skin inflammation while leptin induces a psoriatic phenotype in human keratinocytes. Experimental Dermatology, 338-345. [26(4)].

Schiener, M., Eberlein, B., Moreno Aguilar, C., Pietsch, G., Serrano, P., McIntyre, M., Schwarze, L., Russkamp, D., Biedermann, T., Spillner, E., Darsow, U., Ollert, M., Schmidt-Weber, C. & Blank, S. (2017). Application of recombinant antigen 5 allergens from seven allergy-relevant Hymenoptera species in diagnostics. Allergy: European Journal of Allergy and Clinical Immunology, 72(1), 98-108. https://doi.org/10.1111/all.13000

Cheng, W., Xu, R., Li, D., Bortolini, C., He, J., Dong, MD., Besenbacher, F., Huang, Y. & Chen, M. (2016). Artificial extracellular matrix delivers TGFb1 regulating myofibroblast differentiation. RSC Advances, 6(26), 21922-21928. https://doi.org/10.1039/c5ra26164c

Jakob, T., Blank, S. & Spillner, E. (2017). Benefits and limitations of recombinant allergens in diagnostics of insect venom allergy. In J. Kleine-Tebbe & T. Jakob (Eds.), Molecular Allergy Diagnostics (pp. 341-362). Springer. https://doi.org/10.1007/978-3-319-42499-6_18

Slemming-Adamsen, P., Song, J., Dong, M., Besenbacher, F. & Chen, M. (2015). In Situ Cross-Linked PNIPAM/Gelatin Nanofibers for Thermo-Responsive Drug Release. Macromolecular Materials & Engineering, 300(12), 1226-1231. https://doi.org/10.1002/mame.201500160

Rottboell, L., de Foenss, S., Thomsen, K., Christiansen, H., Andersen, S. M., Dam, T. N., Kjeldsen, C. R. & Stenderup, K. (2015). Exploring valrubicin’s effect on Propionibacterium acnes-induced skin inflammation in vitro and in vivo. Dermatology Reports, 7/3. https://doi.org/10.4081/dr.2015.6246

Lauritsen, S. H., Bertelsen, L. B., Daugård, P., Laustsen, C., Nielsen, N., Nygaard, J. V. & Stødkilde-Jørgensen, H. (2015). Bioreactor for quantification of cell metabolism by MR-hyperpolarization. Biomedical Physics & Engineering Express, 1(4). https://doi.org/10.1088/2057-1976/1/4/047003

Stenderup, K., Kjeldsen, C. R., Shanebeck, K., Brady, W., Van Brunt, MP., King, G., Marelli, M., Slagle, P., Xu, H., Nairn, NW., Johnson, J., Wang, AA., Li, G., Thornton, KC., Dam, T. N. & Grabstein, KH. (2015). AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use-improves psoriasis in a human xenograft transplantation model. Protein Engineering Design and Selection (Print), 28/10, 467-480. [26271488]. https://doi.org/10.1093/protein/gzv034

Andersen, P. O., Stjernholm, T., Kragstrup, T. W., Steenberg, L. R., Johansen, C., Stenderup, K., Iversen, L. & Kjeldsen, C. R. (2015). The role of leptin in psoriasis comprises a proinflammatory response by the dermal fibroblast. British Journal of Dermatology, [26119283]. https://doi.org/10.1111/bjd.13969

Beer, C., Dokkedahl, K. S., Wang, J., Sutherland, D. & Nyengaard, J. R. (2015). Dermal Absorption of Nanomaterials Titanium Dioxide and Zinc Oxide Based Sunscreen: Role of Size and Surface Coating. Miljøstyrelsen.

Bouzinova, E., Olesen, L. Ø. & Wiborg, O. (2015). Non-cognitive behavior associated with development of Alzheimer pathology in APPswePS1dE9 mice and an effect of long-term paroxetine treatment. Poster session presented at Psykiatriens 10. Forskningsdag, Aarhus N, Denmark.

Jakobsen, M. V., Askou, A. L., Dokkedahl, K. S., Kjeldsen, C. R., Dagnæs-Hansen, F., Jensen, T. G., Corydon, T. J., Mikkelsen, J. G. & Aagaard, L. (2015). Efficient in vivo gene transfer to xenotransplanted human skin by lentivirus-mediated, but not by AAV-directed, gene delivery. Poster session presented at Annual Congress The European Society of Gene and Cell Therapy (ESGCT), Helsinki, Finland.

Kang, R., Li, H., Lysdahl, H., Quang Svend Le, D., Chen, M., Xie, L. & Bünger, C. (2017). Cyanoacrylate medical glue application in intervertebral disc annulus defect repair: Mechanical and biocompatible evaluation. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 105(1), 14–20 . https://doi.org/10.1002/jbm.b.33524

Li, Y., Gregersen, H. V., Nygaard, J. V., Cheng, W., Yu, Y., Huang, Y., Dong, M., Besenbacher, F. & Chen, M. (2015). Ultraporous nanofeatured PCL–PEO microfibrous scaffolds enhance cell infiltration, colonization and myofibroblastic differentiation. Nanoscale, 7(36), 14989-14995. https://doi.org/10.1039/c5nr04244e

Madsen, S. P., Johannsen, S. R., Jeppesen, B. R., Nygaard, J. V., Jensen, P. B., Chevallier, J., Julsgaard, B., Balling, P. & Larsen, A. N. (2015). Optimizing Plasmonically Enhanced Upconversion. Poster session presented at SiliconPV 2015, Konstanz , Germany.

Spillner, E. (2015). Diagnostik der Insektengiftallergie: vom Extrakt zum Molekül. Spitzenforschung in der Allergologie, 2015, 92-93.

Jakobsen, M., Askou, A. L., Stenderup, K., Rosada, C., Dagnæs-Hansen, F., Jensen, T. G., Corydon, T. J., Mikkelsen, J. G. & Aagaard, L. (2015). Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin. Human Gene Therapy. Methods, 26(4), 123-33. https://doi.org/10.1089/hgtb.2014.135

Tian, L., Prabhakaran, M., Hu, J., Chen, M., Besenbacher, F. & Ramakrishnaa , S. (2015). Coaxial electrospun poly(lactic acid)/silk fibroin nanofibers incorporated with nerve growth factor support the differentiation of neuronal stem cells. R S C Advances, 5, 49838-49848. https://doi.org/10.1039/C5RA05773F

Frick, M., Fischer, J., Helbing, A., Ruëff, F., Wieczorek, D., Ollert, M., Pfützner, W., Müller, S., Huss-Marp, J., Dorn, B., Biedermann, T., Lidholm, J., Rücker, G., Bantleon, F., Miehe, M., Spillner, E. & Jakob, T. (2016). Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. Journal of Allergy and Clinical Immunology, 138(6), 1663-1671e9. https://doi.org/10.1016/j.jaci.2016.04.024

Kjær, T. N., Thorsen, K., Jessen, N., Stenderup, K. & Pedersen, S. B. (2015). Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. PLOS ONE, 10(5), [e0126599]. https://doi.org/10.1371/journal.pone.0126599

Frick, M., Müller, S., Bantleon, F., Hus-Marp, J., Lidholm, J., Spillner, E. & Jakob, T. (2015). rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom. Allergy: European Journal of Allergy and Clinical Immunology, 70(12), 1665-1668. https://doi.org/10.1111/all.12725

Jensen, R. K., Plum, M., Tjerrild, L., Jakob, T., Spillner, E. & Andersen, G. R. (2015). Structure of the omalizumab Fab. Acta Crystallographica Section F: Structural Biology Communications, 71(Pt 4), 419-426. https://doi.org/10.1107/S2053230X15004100

Li, Y., Femenias, M. R., Yu, Y., Besenbacher, F. & Chen, M. (2015). Delivery of Dexamethasone from electrospun PCL-PEO binary fibers and their effects on inflammation regulation. R S C Advances, 5, 34166-34172. https://doi.org/10.1039/c5ra03099d

Taskin, M. B., Xu, R., Zhao, H., Wang, X., Dong, M., Besenbacher, F. & Chen, M. (2015). Poly(norepinephrine) as a functional bio-interface for neuronal differentiation on electrospun fibers. Physical Chemistry Chemical Physics, 17(14), 9446-53. https://doi.org/10.1039/c5cp00413f

Xu, R., Taskin, M. B., Rubert, M., Seliktar, D., Besenbacher, F. & Chen, M. (2015). hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold. Scientific Reports, 5, 1-7. [8480]. https://doi.org/10.1038/srep08480

Nygaard, J. V. (2015). Notes on the Hyperelasticity of Materials.

Krishna, K., Galsgaard, R., Heide-Jørgensen, S., Bechsgaard, T. K., Zegdi, R., Bräuner, L. E., Nygaard, J. V. & Johansen, P. (2015). The effect of TAVI oversizing on valve tissue stresses. Poster session presented at The 25th Annual Meeting of the Scandinavian Society for Research in Cardiothoracic Surgery, Geilo, Norway.

Möbs, C., Müller, J., Rudzio, A., Pickert, J., Blank, S., Jakob, T., Spillner, E. & Pfützner, W. (2015). Decline of Ves v 5-specific blocking capacity in wasp venom-allergic patients after stopping allergen immunotherapy. Allergy: European Journal of Allergy and Clinical Immunology, 6. https://doi.org/10.1111/all.12606

Lin, L., Cui, H., Zhou, H., Zhang, X., Bortolini, C., Chen, M., Liu, L. & Dong, M. (2015). Nanoliposomes containing Eucalyptus citriodora as antibiotic with specific antimicrobial activity. Chemical Communications, 51(13), 2653-5. https://doi.org/10.1039/c4cc09386k

Rasmussen, M. R., Marqvorsen, M. H. S., Kristensen, S. K. & Jensen, H. H. (2014). A Protocol for Metal Triflate Catalyzed Direct Glycosylations with GalNAc 1-OPiv Donors. Journal of Organic Chemistry, 79(22), 11011-11019. https://doi.org/10.1021/jo502036f

Kang, R., Svend Le, D. Q., Li, H., Lysdahl, H., Chen, M., Besenbacher, F. & Bünger, C. (2013). Engineered three-dimensional nanofibrous multi-lamellar structure for annulus fibrosus repair. Journal of Materials Chemistry B, 1(40), 5462-5468. https://doi.org/10.1039/c3tb20562b, https://doi.org/10.1039/c3tb20562b

Stenderup, K., Rosada, C., Gavillet, B., Vuagniaux, G. & Dam, T. N. (2014). Debio 0932, a new oral Hsp90 inhibitor, alleviates psoriasis in a xenograft transplantation model. Acta Dermato-Venereologica, 94(6), 672-6. https://doi.org/10.2340/00015555-1838

Chen, M., Li, Y. & Besenbacher, F. (2014). Electrospun nanofibers-mediated on-demand drug release. Advanced Healthcare Materials, 3(11), 1721-1732. https://doi.org/10.1002/adhm.201400166

Femenias, M. R., Li, Y., Dehli, J., Taskin, M. B., Besenbacher, F. & Chen, M. (2014). Dexamethasone encapsulated coaxial electrospun PCL/PEO hollow microfibers for inflammation regulation. R S C Advances, 4(93), 51537-51543. https://doi.org/10.1039/C4RA08358J

Femenias, M. R., Dehli, J., Li, Y., Taskin, M. B., Xu, R., Besenbacher, F. & Chen, M. (2014). Electrospun PCL/PEO Coaxial Fibers for basic Fibroblast Growth Factor Delivery. Journal of Materials Chemistry B, 2(48), 8538-8546. https://doi.org/10.1039/C4TB01258E

Rubert, M., Fang-Li, Y., Aslan, H., Yu, Y., Howard, K. A., Dong, MD., Besenbacher, F. & Chen, M. (2014). Inflammatory response of RAW 264.7 cells to ultraporous interweaving PCL-PEO electrospun microfibers. Journal of Tissue Engineering and Regenerative Medicine, 8, 249-249.

Bredehorst, R., Grunwald, T., Ollert, M., Schmidt-Weber, C. & Spillner, E. (2013). Modulation of effector T cell responses by local depletion of complement component C3.

Bredehorst, R., Grunwald, T., Ollert, M., Schmidt-Weber, C. & Spillner, E. (2013). Controlled activation of complement components for use as endogenous adjuvant.

Bantleon, F., Wolf, S., Seismann, H., Dam, S. S., Lorentzen, A., Miehe, M., Jabs, F., Jakob, T., Plum, M. & Spillner, E. (2016). Human IgE is efficiently produced in glycosylated and biologically active form in lepidopteran cells. Molecular Immunology, 72, 49-56. https://doi.org/10.1016/j.molimm.2016.02.013

Bredehorst, R., Grunwald, T., Ollert, M. W., Schmidt-Weber, C. & Spillner, E. (2014). Selective local inhibition of TNFR1-mediated functions at the site of antigen/allergen presentation.

Nygaard, J. V. & Perti, C. (2015). Injectable Hierarchical Scaffolds. (Patent No. PCT/DK2014/050422). http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20150618&CC=WO&NR=2015086029A1&KC=A1

Van Vaerenbergh, M., de Smet, L., Rafei-Shamsabadi, D., Blank, S., Spillner, E., Ebo, D., Devreese, B., Jakob, T. & C. de Graaf, D. (2015). IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology. Molecular Immunology, 63(2), 449-455. https://doi.org/10.1016/j.molimm.2014.09.018

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