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Department of Biological and Chemical Engineering

Publications by Medical Biotechnology

Are you looking for publications by Section of Medical Biotechnology? On this page you can find all the publications made by the Section of Medical Biotechnology - Department of Biological & Chemical Engineering, Aarhus University.

Below you can find a list of all the publications, their publishing date, their author(s), and titles. The list can be sorted by date, author, and title:

List of Publications

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Rafei-Shamsabadi, D., Müller, S., Pfützner, W., Spillner, E., Rueff, F. & Jakob, T. (2014). Recombinant allergens rarely allow identification of Hymenoptera venom-allergic patients with negative specific IgE to whole venom preparations. Journal of Allergy and Clinical Immunology, 134(2), 493-494. https://doi.org/10.1016/j.jaci.2014.05.035

Bredehorst, R., Grunwald, T., Ollert, M. W., Schmidt-Weber, C. & Spillner, E. (2014). Selective local inhibition of TNFR1-mediated functions at the site of antigen/allergen presentation.

Jensen, J., Rölfing, J. H. D., Svend Le, D. Q., Kristiansen, A. A., Nygaard, J. V., Hokland, L. B., Bendtsen, M., Kassem, M., Lysdahl, H. & Bünger, C. (2014). Surface-modified functionalized polycaprolactone scaffolds for bone repair: In vitro and in vivo experiments. Journal of Biomedical Materials Research. Part A, 102(9), 2993-3003. https://doi.org/10.1002/jbm.a.34970

Li, Y. Y., Femenias, M. R., Aslan, H. H., Yu, Y. Y., Howard, K., Dong, MD., Besenbacher, F. F. & Chen, M. M. (2014). Ultraporous interweaving electrospun microfibers from PCL-PEO binary blends and their inflammatory responses. Nanoscale, 6(6), 3392-3402. https://doi.org/10.1039/c3nr06197c

Staunstrup, N. H., Bak, R. O., Cai, Y., Svensson, L., Petersen, A. T., Rosada, C., Stenderup, K., Bolund, L. & Mikkelsen, J. G. (2013). A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin. Experimental Dermatology, 22(3), 178-83. https://doi.org/10.1111/exd.12091

Lin, L., Cui, H., Zeng, G., Chen, M., Zhang, H., Xu, M., Shen, X., Bortolini, C. & Dong, M. (2013). Ag-CuFe2O4 magnetic hollow fibers for recyclable antibacterial materials. Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 1(21), 2719-2723. https://doi.org/10.1039/c3tb20223b

Morgan, S. R., Dooley, E. P., Hocking, P. M., Inglehearn, C. F., Ali, M., Sorensen, T. L-M., Meek, K. M. & Boote, C. (2013). An x-ray scattering study into the structural basis of corneal refractive function in an avian model. Biophysical Journal, 104(12), 2586-94. https://doi.org/10.1016/j.bpj.2013.04.053

Nygaard, J. V. (2013). Combining Imaging Modalities in the Modelling of Multi Parameter Devices. In ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation (FMD2013) (Vol. 2013). [FMD2013-16124] American Society of Mechanical Engineers. https://doi.org/10.1115/FMD2013-16124

Nygaard, J. V. (2013). Combining imaging modalities in the modeling of multiparameter devices. Journal of Medical Devices, Transactions of the ASME, 7(4). https://doi.org/10.1115/1.4025846

Bredehorst, R., Grunwald, T., Ollert, M., Schmidt-Weber, C. & Spillner, E. (2013). Controlled activation of complement components for use as endogenous adjuvant.

Kötzler, M. P., Blank, S., Bantleon, F. I., Wienke, M., Spillner, E. & Meyer, B. (2013). Donor assists acceptor binding and catalysis of human α1,6-fucosyltransferase. A C S Chemical Biology, 8(8), 1830-40. https://doi.org/10.1021/cb400140u

Chen, M., Nielsen, S. R., Uyar, T., Zhang, S., Zafar, A., Dong, M. & Besenbacher, F. (2013). Electrospun UV-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex. Journal of Materials Chemistry, Part C(1), 850-855. https://doi.org/10.1039/c2tc00180b

Kang, R., Svend Le, D. Q., Li, H., Lysdahl, H., Chen, M., Besenbacher, F. & Bünger, C. (2013). Engineered three-dimensional nanofibrous multi-lamellar structure for annulus fibrosus repair. Journal of Materials Chemistry B, 1(40), 5462-5468. https://doi.org/10.1039/c3tb20562b, https://doi.org/10.1039/c3tb20562b

Van Vaerenbergh, M., Cardoen, D., M. Formesyn, E., Brunain, M., Van Driessche, G., Blank, S., Spillner, E., Verleyen, P., Wenseleers, T., Schoofs, L., Devreese, B. & C. de Graaf, D. (2013). Extending the honeybee venome with the antimicrobial peptide apidaecin and a protein resembling wasp antigen 5. Insect Molecular Biology, 22(2), 199-210.

Jiang, Z., Xia, D., Li, Y., Li, J., Li, Q., Chen, M., Huang, Y., Besenbacher, F. & Dong, M. (2013). Facilitating the mechanical properties of a high-performance pH-sensitive membrane by cross-linking graphene oxide and polyacrylic acid. Nanotechnology, 24(33), 335704. https://doi.org/10.1088/0957-4484/24/33/335704

Jiang, Z., Li, Q., Chen, M., Li, J., Li, J., Huang, Y., Besenbacher, F. & Dong, M. (2013). Mechanical reinforcement fibers produced by gel-spinning of poly-acrylic acid (PAA) and graphene oxide (GO) composites. Nanoscale, 5(14), 6265-6269. https://doi.org/10.1039/c3nr00288h

Bredehorst, R., Grunwald, T., Ollert, M., Schmidt-Weber, C. & Spillner, E. (2013). Modulation of effector T cell responses by local depletion of complement component C3.

Nielsen, S. R., Besenbacher, F. & Chen, M. (2013). Mussel inspired surface functionalization of electrospun nanofibers for bio-applications. Physical Chemistry Chemical Physics, 15(40). https://doi.org/10.1039/c3cp52651h

Antaloae, A. V., Montigny, C., le Maire, M., Watson, K. A. & Sørensen, T. L-M. (2013). Optimisation of recombinant production of active human cardiac SERCA2a ATPase. PLOS ONE, 8(8), e71842. https://doi.org/10.1371/journal.pone.0071842

Blank, S., Neu, C., Hasche, D., Bantleon, F. I., Jakob, T. & Spillner, E. (2013). Polistes species venom is devoid of carbohydrate-based cross-reactivity and allows interference-free diagnostics. The Journal of allergy and clinical immunology, 131(4), 1239-42. https://doi.org/10.1016/j.jaci.2012.10.047

Boote, C., Dooley, E. P., Gardner, S. J., Kamma-Lorger, C. S., Hayes, S., Nielsen, K., Hjortdal, J., Sørensen, T. L-M., Terrill, N. J. & Meek, K. M. (2013). Quantification of collagen ultrastructure after penetrating keratoplasty - implications for corneal biomechanics. PLOS ONE, 8(7), e68166. https://doi.org/10.1371/journal.pone.0068166

Andersen, M. Ø., Le, D. Q. S., Chen, M., Nygaard, J. V., Kassem, M., Bünger, C. & Kjems, J. (2013). Spatially Controlled Delivery of siRNAs to Stem Cells in Implants Generated by Multi-Component Additive Manufacturing. Advanced Functional Materials, 23(45), 5599-5607. https://doi.org/10.1002/adfm.201300832

Laugesen, I. G., Hauge, E., Andersen, S. M., Stenderup, K., de Darkó, E., Dam, T. N. & Rosada, C. (2013). Valrubicin activates PKCa in keratinocytes: a conceivable mode of action in treating hyper-proliferative skin diseases. Journal of Drugs in Dermatology, 12(10), 1156-62.

Blank, S., Seismann, H., McIntyre, M., Ollert, M., Wolf, S., Bantleon, F. I. & Spillner, E. (2013). Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom. P L o S One, 8(4). https://doi.org/10.1371/journal.pone.0062009

Christensen, B. B., Foldager, C. B., Hansen, O. M., Kristiansen, A. A., Le, D. Q. S., Nielsen, A. D., Nygaard, J. V., Bünger, C. E. & Lind, M. (2012). A novel nano-structured porous polycaprolactone scaffold improves hyaline cartilage repair in a rabbit model compared to a collagen type I/III scaffold: in vitro and in vivo studies. Knee Surgery, Sports Traumatology, Arthroscopy, 20(6), 1192-204. https://doi.org/10.1007/s00167-011-1692-9

Wehr, C., Müller, F., Schüler, J., Tomann, T., Nitschke, C., Seismann, H., Spillner, E., Klingner, K., Schneider-Merck, T., Binder, M., Fiebig, H-H., Mertelsmann, R. & Trepel, M. (2012). Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model. International Journal of Cancer, 131(2), E10-20. https://doi.org/10.1002/ijc.26464

Spillner, E., Greunke, K., Seismann, H., Blank, S., Braren, I. & du Plessis, D. (2012). Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy. Biologicals, 40(5), 313-322. https://doi.org/10.1016/j.biologicals.2012.05.003

Nygaard, J. V. (2012). CFD - flow induced structural vibrations.

Nygaard, J. V. (2012). CFD i fysiokemisk hydrodynamik - transport og reaktionsstrømning.

Chen, M., Gao, S., Dong, M., Song, J., Yang, C., Howard, K. A., Kjems, J. & Besenbacher, F. (2012). Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery. A C S Nano, 6(6), 4835-4844. https://doi.org/10.1021/nn300106t

Jakob, T., Köhler, J., Blank, S., Spillner, E., Magnusson, U., Lidholm, J. & Huss-Marp, J. (2012). Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant-negative patients with bee venom allergy. Journal of Allergy and Clinical Immunology, 130(1), 276-278. https://doi.org/10.1016/j.jaci.2012.03.048

Niemann, A. K., Thrysoe, S., Nygaard, J. V., Hasenkam, M. & Petersen, S. E. (2012). Computational Fluid Dynamics simulation of a-v fistulas: From MRI and ultrasound scans to numeric evaluation of hemodynamics. Journal of Vascular Access, 13(1), 36-44. https://doi.org/10.5301/JVA.2011.8440

Hayes, S., Khan, S., Boote, C., Kamma-Lorger, C. S., Dooley, E., Lewis, J., Hawksworth, N., Sorensen, T., Daya, S. & Meek, K. M. (2012). Depth profile study of abnormal collagen orientation in keratoconus corneas. JAMA Ophthalmology, 130(2), 251-2. https://doi.org/10.1001/archopthalmol.2011.1467

Kötzler, M. P., Blank, S., Bantleon, F. I., Spillner, E. & Meyer, B. (2012). Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8). B B A - General Subjects, 1820(12), 1915-1925. https://doi.org/10.1016/j.bbagen.2012.08.018

Song, J., Kahveci, D., Chen, M., Guo, Z., Xie, E., Xu, X., Besenbacher, F. & Dong, M. (2012). Enhanced Catalytic Activity of Lipase Encapsulated in PCL Nanofibers. Langmuir, 28. https://doi.org/10.1021/la300469s

Chen, M., Le, D. Q. S., Hein, S., Li, P., Nygaard, J. V., Kassem, M., Kjems, J., Besenbacher, F. & Bünger, C. (2012). Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release. International Journal of Nanomedicine (Online), (7), 4285-97. https://doi.org/10.2147/IJN.S33083

Kötzler, M. P., Blank, S., Behnken, H. N., Alpers, D., Bantleon, F. I., Spillner, E. & Meyer, B. (2012). Formation of the immunogenic α1,3-fucose epitope: elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A. Insect Biochemistry and Molecular Biology, 42(2), 116-25. https://doi.org/10.1016/j.ibmb.2011.11.004

Nygaard, J. V. (2012). Mekanisk Design af Implantater og Apparater.

Spillner, E., Blank, S. & Jakob, T. (2012). Potenzial, Fallstricke und aktueller Status der molekularen Diagnostik am Beispiel der Insektengiftallergie. Allergo Journal, 21(4), 249-256. https://doi.org/10.1007/s15007-012-0128-2

Pijanka, J. K., Coudrillier, B., Ziegler, K., Sorensen, T., Meek, K. M., Nguyen, T. D., Quigley, H. A. & Boote, C. (2012). Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae. Investigative Ophthalmology & Visual Science, 53(9), 5258-70. https://doi.org/10.1167/iovs.12-9705

Song, J., Chen, M., Regina, V. R., Wang, C., Meyer, R. L., Xie, E., Wang, C., Besenbacher, F. & Dong, M. (2012). Safe and Effective Ag Nanoparticles Immobilized Antimicrobial NanoNonwovens. Advanced Engineering Materials. https://doi.org/10.1002/adem.201180085

Thrysøe, S. A., Stegmann, A. F., Eldrup, N., Klærke, A., Paaske, W., Kim, W. Y. & Nygaard, J. V. (2012). The Effect of Carotid Plaque Morphology on Longitudinal Fibrous Cap Stress Levels. World Journal of Mechanics, 2, 216-223. https://doi.org/10.4236/wjm.2012.24026

Blank, S., Bantleon, F. I., Ollert, M., McIntyre, M. & Spillner, E. (2012). The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity. Clinical and Experimental Allergy, 42(6), 976-985. https://doi.org/10.1111/j.1365-2222.2012.03966.x

Michel, Y., Ginglinger, H., Blank, S., McIntyre, M., Ollert, M., Cifuentes, L. & Spillner, E. (2012). The putative serine protease inhibitor Api m 6 from Apis Mellifera venom: Recombinant and structural evaluation. Journal of Investigational Allergology and Clinical Immunology, 22(7), 476-484.

Hauge, E., Christiansen, H., Rosada, C., de Darkó, E., Dam, T. N. & Stenderup, K. (2012). Topical valrubicin application reduces skin inflammation in murine models. British Journal of Dermatology, 167(2), 288-95. https://doi.org/10.1111/j.1365-2133.2012.10964.x

Wittenborn, T., Nielsen, T., Nygaard, J. V., Larsen, E. K. U., Thim, T., Rydtoft, L. M., Vorup-Jensen, T., Kjems, J., Nielsen, N. C., Horsman, M. R. & Falk, E. (2012). Ultra-High-Field DCE-MRI of Angiogenesis in a Novel Angiogenesis Mouse Model. Journal of Magnetic Resonance Imaging, 35(3), 703-710. https://doi.org/10.1002/jmri.22855

Nygaard, J. V., Foss, M., Cloetens, P., Andersen, M. Ø., Kassem, M., Kjems, J. & Besenbacher, F. (2011). 3D deformation in nanoporous system for tissue phenotype emergence through stem cell specification. http://www.wksp-MBiomech.dem.ist.utl.pt

Thrysøe, S. A. & Nygaard, J. V. (2011). Active Pumping in Endothelial Cell Tight Junctions. Poster session presented at Biomechanics in vascular Biology and Cardiovascular Disease, Rotterdam, Netherlands.

Blank, S., Seismann, H., Michel, Y., McIntyre, M., Cifuentes, L., Braren, I., Grunwald, T., Darsow, U., Ring, J., Bredehorst, R., Ollert, M. & Spillner, E. (2011). Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts. Allergy: European Journal of Allergy and Clinical Immunology, 66(10), 1322-1329. https://doi.org/10.1111/j.1398-9995.2011.02667.x

Nygaard, J. V., Uyar, T., Chen, M., Cloetens, P., Kingshott, P. & Besenbacher, F. (2011). Characterisation of internal morphologies in electrospun fibers by X-ray tomographic microscopy. Nanoscale, 3. https://doi.org/10.1039/c1nr10304k

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Revised 21.11.2022

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