This presentation will focus on my Master's thesis, where I am utilizing melt-electrowriting to fabricate porous filters of polycaprolactone (PCL). The fiber surface is subsequently conjugated with an anti-EpCAM antibody to allow for affinity-based capture of rare circulating tumor cells (CTCs) from a liquid biopsy, i.e. a blood sample. Due to the biocompatibility of PCL, the caught CTCs will be cultured ex vivo directly on the filter and the formed clusters may contain information useful for personalized medicine.