Schmid, J. M., Skjold, T., Kolstad, H. A., Miehe, M., Spillner, E. & Hoffmann, H. J. (2019).
Work-related allergic asthma: Clinical work-up of a 45-year old male working in animal feed producing industry.
Allergy: European Journal of Allergy and Clinical Immunology,
74, 316-316.
Blank, S., Seismann, H., McIntyre, M., Ollert, M., Wolf, S., Bantleon, F. I.
& Spillner, E. (2013).
Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom.
P L o S One,
8(4).
https://doi.org/10.1371/journal.pone.0062009
Riverol, A. P.
, Miehe, M., Jabs, F., Seismann, H., Romani Fernandes, L. G., de Lima Zollner, R., Jakob, T., Brochetto-Braga, M. R.
& Spillner, E. (2018).
Venoms of Neotropical wasps lack cross-reactive carbohydrate determinants enabling reliable protein-based specific IgE determination.
Journal of Allergy and Clinical Immunology,
141(5), 1917-1919.e1.
https://doi.org/10.1016/j.jaci.2017.12.990
Kolln, J., Ren, H.-M., Da, R.-R., Zhang, Y.
, Spillner, E., Olek, M., Hermanowicz, N., Hilgenberg, L. G., Smith, M. A., van den Noort, S. & Qin, Y. (2006).
Triosephosphate isomerase- and glyceraldehyde-3-phosphate dehydrogenase-reactive autoantibodies in the cerebrospinal fluid of patients with multiple sclerosis.
Journal of Immunology,
177(8), 5652-8.
Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B.
, Miehe, M., Mandolesi, M., Rauber, M. M., Pfützner, W., Jakob, T., Möbs, C.
, Andersen, G. R. & Spillner, E. (2018).
Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction.
Nature Communications,
9(1), Artikel 7.
https://doi.org/10.1038/s41467-017-02312-7
Michel, Y., Ginglinger, H., Blank, S., McIntyre, M., Ollert, M., Cifuentes, L.
& Spillner, E. (2012).
The putative serine protease inhibitor Api m 6 from Apis Mellifera venom: Recombinant and structural evaluation.
Journal of Investigational Allergology and Clinical Immunology,
22(7), 476-484.
Blank, S., Bantleon, F. I., Ollert, M., McIntyre, M.
& Spillner, E. (2012).
The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components of Apis mellifera venom with allergenic potential beyond carbohydrate-based reactivity.
Clinical and Experimental Allergy,
42(6), 976-985.
https://doi.org/10.1111/j.1365-2222.2012.03966.x
Jakob, T., Rauber, M. M., Perez-Riverol, A.
, Spillner, E. & Blank, S. (2020).
The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy.
Current Allergy and Asthma Reports,
20(9), Artikel 48.
https://doi.org/10.1007/s11882-020-00943-3
Rauber, M., Roßbach, A., Jung, A., Müller, S., Möbs, C., Pfützner, W.
, Miehe, M., Spillner, E. & Jakob, T. (2020).
The honey bee venom allergen Api m 10 displays one major IgE epitope, Api m 10160-174.
Allergy: European Journal of Allergy and Clinical Immunology,
75(7), 1756-1759.
https://doi.org/10.1111/all.14187
Pourjafar, M., Saidijam, M.
, Miehe, M., Najafi, R., Soleimani, M.
& Spillner, E. (2023).
Surfaceome Profiling Suggests Potential of Anti-MUC1×EGFR Bispecific Antibody for Breast Cancer Targeted Therapy.
Journal of Immunotherapy,
46(7), 245-261.
https://doi.org/10.1097/CJI.0000000000000482
Spillner, E., Laursen, N. S., Andersen, K. R., Sottrup-Jensen, L., Andersen, G. R. & Braren, I. (2011).
Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
E M B O Journal,
30(3), 606-616.
https://doi.org/10.1038/emboj.2010.341
Jensen, R. K., Plum, M., Tjerrild, L., Jakob, T.
, Spillner, E. & Andersen, G. R. (2015).
Structure of the omalizumab Fab.
Acta Crystallographica Section F: Structural Biology Communications,
71(Pt 4), 419-426.
https://doi.org/10.1107/S2053230X15004100
Jensen, R. K., Jabs, F.
, Miehe, M., Mølgaard, B., Pfützner, W., Möbs, C.
, Spillner, E. & Andersen, G. R. (2020).
Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy.
Allergy: European Journal of Allergy and Clinical Immunology,
75(8), 1952-1961.
https://doi.org/10.1111/all.14222
Spillner, E., Laursen, N. S., Christensen, J. B., Jensen, M., Fredslund, F., Sottrup-Jensen, L., Andersen, G. R., Gordon, N., Hermans, S., Lorenz, N., Jackson, N., Fraser, J. D., Wines, B. & Bjerre, M. (2010).
Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus.
Proceedings of the National Academy of Sciences,
107(8), 3681-3686.
https://doi.org/10.1073/pnas.0910565107
Plum, M., Tjerrild, L., Raiber, T., Bantleon, F., Bantleon, S.
, Miehe, M., Jabs, F., Seismann, H., Möbs, C., Pfützner, W., Jakob, T.
, Andersen, G. R. & Spillner, E. (2023).
Structural and functional analyses of antibodies specific for modified core N-glycans suggest a role in TH2 responses.
Allergy,
78(1), 121-130.
https://doi.org/10.1111/all.15417
Binder, M., Léchenne, B., Ummanni, R., Balabanov, S., Trepel, M., Scharf, C., Trusch, M., Schlüter, H., Braren, I.
& Spillner, E. (2010).
Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells.
P L o S One,
5(12), Artikel e15992.
https://doi.org/10.1371/journal.pone.0015992
Hofmann, S. C., Pfender, N., Weckesser, S., Jakob, T., Blank, S.
, Spillner, E. & Huss-Marp, J. (2011).
Reply.
Journal of Allergy and Clinical Immunology,
128(1), 248.
https://doi.org/10.1016/j.jaci.2011.02.020
Seismann, H., Blank, S., Cifuentes, L., Braren, I., Bredehorst, R., Grunwald, T., Ollert, M.
& Spillner, E. (2010).
Recombinant phospholipase A1 (Ves v 1) from yellow jacket venom for improved diagnosis of hymenoptera venom hypersensitivity.
Clinical and Molecular Allergy,
8.
https://doi.org/10.1186/1476-7961-8-7
Greunke, K., Braren, I., Alpers, I., Blank, S., Sodenkamp, J., Bredehorst, R.
& Spillner, E. (2008).
Recombinant IgY for improvement of immunoglobulin-based analytical applications.
Clinical Biochemistry,
41(14-15), 1237-44.
https://doi.org/10.1016/j.clinbiochem.2008.07.004
Spillner, E., Plum, M., Blank, S.
, Miehe, M., Singer, J. & Braren, I. (2012).
Recombinant IgE antibody engineering to target EGFR.
Cancer Immunology, Immunotherapy,
61(9), 1565-73.
https://doi.org/10.1007/s00262-012-1287-4
Rafei-Shamsabadi, D., Müller, S., Pfützner, W.
, Spillner, E., Rueff, F. & Jakob, T. (2014).
Recombinant allergens rarely allow identification of Hymenoptera venom-allergic patients with negative specific IgE to whole venom preparations.
Journal of Allergy and Clinical Immunology,
134(2), 493-494.
https://doi.org/10.1016/j.jaci.2014.05.035
Frick, M., Müller, S., Bantleon, F., Hus-Marp, J., Lidholm, J.
, Spillner, E. & Jakob, T. (2015).
rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom.
Allergy: European Journal of Allergy and Clinical Immunology,
70(12), 1665-1668.
https://doi.org/10.1111/all.12725
Łoś, M., Łoś, J. M., Blohm, L.
, Spillner, E., Grunwald, T., Albers, J., Hintsche, R. & Wegrzyn, G. (2005).
Rapid detection of viruses using electrical biochips and anti-virion sera.
Letters in Applied Microbiology,
40(6), 479-85.
https://doi.org/10.1111/j.1472-765X.2005.01706.x
Braren, I., Greunke, K., Grunwald, T., Pilette, C., Mempel, M., Bredehorst, R., Ring, J.
, Spillner, E. & Ollert, M. (2011).
Quantitation of serum IgE by using chimeras of human IgE receptor and avian immunoglobulin domains.
Analytical Biochemistry,
412(2), 134-140.
https://doi.org/10.1016/j.ab.2010.12.013
Frick, M., Fischer, J., Helbing, A., Ruëff, F., Wieczorek, D., Ollert, M., Pfützner, W., Müller, S., Huss-Marp, J., Dorn, B., Biedermann, T., Lidholm, J., Rücker, G., Bantleon, F.
, Miehe, M., Spillner, E. & Jakob, T. (2016).
Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy.
Journal of Allergy and Clinical Immunology,
138(6), 1663-1671e9.
https://doi.org/10.1016/j.jaci.2016.04.024
Blank, S., Neu, C., Hasche, D., Bantleon, F. I., Jakob, T.
& Spillner, E. (2013).
Polistes species venom is devoid of carbohydrate-based cross-reactivity and allows interference-free diagnostics.
The Journal of allergy and clinical immunology,
131(4), 1239-42.
https://doi.org/10.1016/j.jaci.2012.10.047
Perez Riverol, A., Romani Fernandes, L. G., Musacchio Lasa, A., Aparecido dos Santos-Pinto, J. R., Moitinho Abram, D., Izuka Moraes, G. H., Jabs, F.
, Miehe, M., Seismann, H., Sergio Palma, M., de Lima Zollner, R.
, Spillner, E. & Brochetto-Braga, M. R. (2018).
Phospholipase A1-based cross-reactivity among venoms of clinically relevant Hymenoptera from Neotropical and temperate regions.
Molecular Immunology,
93, 87-93.
https://doi.org/10.1016/j.molimm.2017.11.007
Pedersen, C. T., Loke, I., Lorentzen, A., Wolf, S., Kamble, M., Kristensen, S. K., Munch, D.
, Radutoiu, S., Spillner, E., Roepstorff, P., Thaysen-Andersen, M.
, Stougaard, J. & Dam, S. (2017).
N-glycan maturation mutants in Lotus japonicus for basic and applied glycoprotein research.
Plant Journal,
91(3), 394-407.
https://doi.org/10.1111/tpj.13570
Aagaard, J. B., Sivelle, C., Fischer, M., Byskov, K., Laursen, N. S., Pfützner, W., Jakob, T., Möbs, C.
, Miehe, M. & Spillner, E. (2022).
Nanobody-based human antibody formats act as IgE surrogate in hymenoptera venom allergy.
Allergy: European Journal of Allergy and Clinical Immunology,
77(9), 2859-2862.
https://doi.org/10.1111/all.15391
Grunwald, T., Bockisch, B.
, Spillner, E., Bredehorst, R., Ring, J. & Ollert, M. W. (2006).
Molecular cloning and expression in insect cells of honeybee venom allergen acid phosphatase (Api m 3).
Journal of Allergy and Clinical Immunology,
117(4), 848-854.
https://doi.org/10.1016/j.jaci.2005.12.1331
Gorjanović, S., Beljanski, M. V., Pavlović, M.
, Spillner, E., Gorjanović, R. & Gojgić-Cvijanović, G. (2005).
Malting barley grain non-specific lipid-transfer protein (ns-LTP): Importance for grain protection.
Journal of the Institute of Brewing,
111(2), 99-104.
Sonnenberg-Riethmacher, E., Wüstefeld, T.
, Miehe, M., Trautwein, C. & Riethmacher, D. (2007).
Maid (GCIP) is involved in cell cycle control of hepatocytes. Hepatology,
45(2), 404.
Strecker, C., Bärenfänger, M.
, Miehe, M., Spillner, E. & Meyer, B. (2020).
In Silico Evaluation of the Binding Site of Fucosyltransferase 8 and First Attempts to Synthesize an Inhibitor with Drug-Like Properties.
ChemBioChem,
21(13), 1923-1931.
https://doi.org/10.1002/cbic.201900289
Vos, B. J. P. R., Dubois, A. E. J., Rauber, M. M., Pfützner, W.
, Miehe, M., Bohle, B., Möbs, C. & Oude Elberink, J. N. G. (2019).
Initiating yellow jacket venom immunotherapy with a 100-μg dose: A challenge? Journal of Allergy and Clinical Immunology: In Practice,
7(4), 1332-1334.e4.
https://doi.org/10.1016/j.jaip.2018.09.005