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Vitreoscilla hemoglobin expression in engineered Escherichia coli: Improved performance in high cell-density batch cultivations.
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Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures.
Biotechnology and Bioengineering,
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Transport-controlled growth decoupling for self-induced protein expression with a glycerol-repressible genetic circuit.
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Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system.
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Toward efficient microaerobic processes using engineered Escherichia coli W3110 strains.
Engineering in Life Sciences,
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Sigma Factors as Potential Targets to Enhance Recombinant Protein Expression.
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Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rate.
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Recombinant protein expression in proteome-reduced cells under aerobic and oxygen-limited regimes.
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Plasmid DNA production in proteome-reduced Escherichia coli.
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Physiological effects of pH gradients on Escherichia coli during plasmid DNA production.
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Physiological and transcriptional comparison of acetate catabolism between Acinetobacter schindleri ACE and Escherichia coli JM101.
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Modification of glucose import capacity in Escherichia coli: Physiologic consequences and utility for improving DNA vaccine production.
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Microbial population heterogeneity versus bioreactor heterogeneity: Evaluation of Redox Sensor Green as an exogenous metabolic biosensor.
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Metabolic variability in bioprocessing: Implications of microbial phenotypic heterogeneity.
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Metabolic modeling and response surface analysis of an Escherichia coli strain engineered for shikimic acid production.
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Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis.
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Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered E. coli.
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Inactivation of pyruvate kinase or the phosphoenolpyruvate: Sugar phosphotransferase system increases shikimic and dehydroshikimic acid yields from glucose in bacillus subtilis.
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High kanamycin concentration as another stress factor additional to temperature to increase pdna production in e. Coli dh5α batch and fed-batch cultures.
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High cell-density processes in batch mode of a genetically engineered Escherichia coli strain with minimized overflow metabolism using a pressurized bioreactor.
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High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism.
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Heterogeneous oxygen availability affects the titer and topology but not the fidelity of plasmid DNA produced by Escherichia coli.
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Glucose transport engineering allows mimicking fed-batch performance in batch mode and selection of superior producer strains.
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Glucose consumption rate-dependent transcriptome profiling of Escherichia coli provides insight on performance as microbial factories.
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Genomic and physiological characterization of a laboratory-isolated Acinetobacter schindleri ACE strain that quickly and efficiently catabolizes acetate.
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Furfural biotransformation in Acinetobacter baylyi ADP1 and Acinetobacter schindleri ACE.
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Fast dynamic response of the fermentative metabolism of Escherichia coli to aerobic and anaerobic glucose pulses.
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Evaluation of microbial globin promoters for oxygen-limited processes using Escherichia coli.
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Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategies.
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Enhanced production of plasmid DNA by engineered Escherichia coli strains.
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Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode.
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Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditions.
Biotechnology and Bioengineering,
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Engineering E. coli for improved microaerobic pDNA production.
Bioprocess and Biosystems Engineering,
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Effect of the oxygen transfer rate on oxygen-limited production of plasmid DNA by Escherichia coli.
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Effect of growth rate on plasmid DNA production and metabolic performance ofengineered Escherichia coli strains.
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